The aryl hydrocarbon receptor: A predominant mediator for the toxicity of emerging dioxin-like compounds

W Zhang, HQ Xie, Y Li, M Zhou, Z Zhou, R Wang… - Journal of hazardous …, 2022 - Elsevier
The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix/Per-ARNT-
Sim (bHLH-PAS) family of transcription factors and has broad biological functions. Early after …

AhR and cancer: from gene profiling to targeted therapy

A Paris, N Tardif, MD Galibert, S Corre - International journal of molecular …, 2021 - mdpi.com
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been
shown to be an essential regulator of a broad spectrum of biological activities required for …

Recent advances in the development of AHR antagonists in immuno-oncology

L Sun - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
The arylhydrocarbon receptor (AHR) is a ligand activated transcription factor that controls
the expression of a number of immunosuppressive signaling molecules, including the …

Psoralen and isopsoralen from Psoraleae Fructus aroused hepatotoxicity via induction of aryl hydrocarbon receptor-mediated CYP1A2 expression

C Zhang, JQ Zhao, JX Sun, HJ Li - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Psoraleae Fructus (PF), a traditional Chinese
medicine, has long been used to treat diseases such as cancer, osteoporosis and …

The immune response of a warm water fish orange-spotted grouper (Epinephelus coioides) infected with a typical cold water bacterial pathogen Aeromonas …

L Huang, W Qi, Y Zuo, SA Alias, W Xu - Developmental & Comparative …, 2020 - Elsevier
The present study reported the first pathogenic Aeromonas salmonicida (SRW-OG1)
isolated from the warm water fish orange-spotted grouper (Epinephelus coioides), and …

The aryl hydrocarbon receptor: a diagnostic and therapeutic target in glioma

TX Lim, M Ahamed, DC Reutens - Drug Discovery Today, 2022 - Elsevier
Glioblastoma multiforme (GBM) is a deadly disease; 5-year survival rates have shown little
improvement over the past 30 years. In vivo positron emission tomography (PET) imaging is …

[引用][C] Development and preclinical evaluation of PET radioligands targeting the aryl hydrocarbon receptor in glioblastoma

TX Lim - 2024 - espace.library.uq.edu.au
Positron emission tomography (PET) is an ingenious imaging tool that can give a glimpse
into the body's inner workings without invasive procedures. Since the inception of the tracer …