Capsaicin: current understanding of its mechanisms and therapy of pain and other pre-clinical and clinical uses
V Fattori, MSN Hohmann, AC Rossaneis… - Molecules, 2016 - mdpi.com
In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …
[HTML][HTML] Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain
Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
Brain mechanisms mediating effects of stress on reward sensitivity
Highlights•Stress preferentially perturbates reward anticipation (rather than
consumption).•Cortico–striatal–limbic network dysregulation subserves stress effects on …
consumption).•Cortico–striatal–limbic network dysregulation subserves stress effects on …
Awake mouse imaging: from two-photon microscopy to blood oxygen level–dependent functional magnetic resonance imaging
Background Functional magnetic resonance imaging (fMRI) in awake behaving mice is well
positioned to bridge the detailed cellular-level view of brain activity, which has become …
positioned to bridge the detailed cellular-level view of brain activity, which has become …
Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
Ginger extract and its compound, 6-shogaol, attenuates painful diabetic neuropathy in mice via reducing TRPV1 and NMDAR2B expressions in the spinal cord
Ethnopharmacological relevance In silico data revealed that the active compound of ginger
(Zingiber officinale Roscoe), 6-shogaol, has strong affinity toward transient receptor potential …
(Zingiber officinale Roscoe), 6-shogaol, has strong affinity toward transient receptor potential …
Applications in awake animal magnetic resonance imaging
CF Ferris - Frontiers in neuroscience, 2022 - frontiersin.org
There are numerous publications on methods and applications for awake functional MRI
across different species, eg, voles, rabbits, cats, dogs, and rhesus macaques. Each of these …
across different species, eg, voles, rabbits, cats, dogs, and rhesus macaques. Each of these …
Where do we stand on fMRI in awake mice?
Imaging awake animals is quickly gaining traction in neuroscience as it offers a means to
eliminate the confounding effects of anesthesia, difficulties of inter-species translation (when …
eliminate the confounding effects of anesthesia, difficulties of inter-species translation (when …
Primary role of the amygdala in spontaneous inflammatory pain-associated activation of pain networks–a chemogenetic manganese-enhanced MRI approach
D Arimura, K Shinohara, Y Takahashi… - Frontiers in Neural …, 2019 - frontiersin.org
Chronic pain is a major health problem, affecting 10–30% of the population in developed
countries. While chronic pain is defined as “a persistent complaint of pain lasting for more …
countries. While chronic pain is defined as “a persistent complaint of pain lasting for more …
Characterization of incisional and inflammatory pain in rats using functional tools of MRI
S Amirmohseni, D Segelcke, S Reichl, L Wachsmuth… - Neuroimage, 2016 - Elsevier
Underlying mechanisms of hyperalgesia differ with regard to the pain entities, which are well-
modeled in animals for systematic studies. However, neuroimaging in different animal pain …
modeled in animals for systematic studies. However, neuroimaging in different animal pain …