NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology
The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …
identified in the membrane of phagocytic cells. For many years, its only known role was in …
[HTML][HTML] Architecture of the NADPH oxidase family of enzymes
BC Ogboo, UV Grabovyy, A Maini, S Scouten… - Redox Biology, 2022 - Elsevier
Abstract The NADPH Oxidases (NOX) catalyze the deliberate production of reactive oxygen
species (ROS) and are established regulators of redox-dependent processes across diverse …
species (ROS) and are established regulators of redox-dependent processes across diverse …
Structure of the core human NADPH oxidase NOX2
NOX2 is the prototypical member of the NADPH oxidase NOX superfamily and produces
superoxide (O2•−), a key reactive oxygen species (ROS) that is essential in innate and …
superoxide (O2•−), a key reactive oxygen species (ROS) that is essential in innate and …
NADPH oxidases: from molecular mechanisms to current inhibitors
A Cipriano, M Viviano, A Feoli, C Milite… - Journal of medicinal …, 2023 - ACS Publications
NADPH oxidases (NOXs) form a family of electron-transporting membrane enzymes whose
main function is reactive oxygen species (ROS) generation. Strong evidence suggests that …
main function is reactive oxygen species (ROS) generation. Strong evidence suggests that …
Structure of human phagocyte NADPH oxidase in the resting state
Phagocyte oxidase plays an essential role in the first line of host defense against pathogens.
It oxidizes intracellular NADPH to reduce extracellular oxygen to produce superoxide anions …
It oxidizes intracellular NADPH to reduce extracellular oxygen to produce superoxide anions …
Structure of human phagocyte NADPH oxidase in the activated state
Phagocyte NADPH oxidase, a protein complex with a core made up of NOX2 and p22
subunits, is responsible for transferring electrons from intracellular NADPH to extracellular …
subunits, is responsible for transferring electrons from intracellular NADPH to extracellular …
Structures of human dual oxidase 1 complex in low-calcium and high-calcium states
Dual oxidases (DUOXs) produce hydrogen peroxide by transferring electrons from
intracellular NADPH to extracellular oxygen. They are involved in many crucial biological …
intracellular NADPH to extracellular oxygen. They are involved in many crucial biological …
High-throughput screening of caterpillars as a platform to study host–microbe interactions and enteric immunity
AG Windfelder, FHH Müller, B Mc Larney… - Nature …, 2022 - nature.com
Mammalian models of human disease are expensive and subject to ethical restrictions.
Here, we present an independent platform for high-throughput screening, using larvae of the …
Here, we present an independent platform for high-throughput screening, using larvae of the …
Development and verification of a prognostic ferroptosis-related gene model in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is the subtype with the worst prognosis of breast
cancer. Ferroptosis, a novel iron-dependent programmed cell death, has an increasingly …
cancer. Ferroptosis, a novel iron-dependent programmed cell death, has an increasingly …
Antioxidant, Collagenase Inhibitory, and Antibacterial Effects of Bioactive Peptides Derived from Enzymatic Hydrolysate of Ulva australis
YA Kang, YJ Kim, SK Jin, HJ Choi - Marine Drugs, 2023 - mdpi.com
The protein extract of Ulva australis hydrolyzed with Alcalase and Flavourzyme was found to
have multi-functional properties, including total antioxidant capacity (TAC), collagenase …
have multi-functional properties, including total antioxidant capacity (TAC), collagenase …