The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation
RG Pestell, C Albanese, AT Reutens… - Endocrine …, 1999 - academic.oup.com
A. Single-transmembrane segment receptors B. Seven-transmembrane receptors C. Steroid
hormones D. Intracellular second messengers IV. Cyclins and CKIs in Endocrine Tumors A …
hormones D. Intracellular second messengers IV. Cyclins and CKIs in Endocrine Tumors A …
TAFs mediate transcriptional activation and promoter selectivity
CP Verrijzer, R Tjian - Trends in biochemical sciences, 1996 - cell.com
The TATA-binding protein (TBP)-associated factors (TAFs) of TFIID play a central role in
RNA polymerase II transcriptional regulation. Some TAFs can function as coactivators that …
RNA polymerase II transcriptional regulation. Some TAFs can function as coactivators that …
brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2
JW Tamkun, R Deuring, MP Scott, M Kissinger… - Cell, 1992 - cell.com
The brahma (brm) gene is required for the activation of multiple homeotic genes in
Drosophila. Loss-offunction brm mutations suppress mutations in Polycomb, a repressor of …
Drosophila. Loss-offunction brm mutations suppress mutations in Polycomb, a repressor of …
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.
R Eckner, ME Ewen, D Newsome… - Genes & …, 1994 - genesdev.cshlp.org
The growth-controlling functions of the adenovirus E1A oncoprotein depend on its ability ot
interact with a set of cellular proteins. Among these are the retinoblastoma protein, p107 …
interact with a set of cellular proteins. Among these are the retinoblastoma protein, p107 …
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins.
Identification of conserved domains or motifs in proteins may aid in the localization and
analysis of important structural and functional regions. We report here a protein sequence …
analysis of important structural and functional regions. We report here a protein sequence …
FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor
H Nakajima, YB Kim, H Terano, M Yoshida… - Experimental cell …, 1998 - Elsevier
Screening for microbial metabolites that induce transcriptional activation of the SV40
promoter resulted in the identification of two known compounds, FR901228 and trichostatin …
promoter resulted in the identification of two known compounds, FR901228 and trichostatin …
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel‐associated box in human synovial sarcoma.
AJ Crew, J Clark, C Fisher, S Gill, R Grimer… - The EMBO …, 1995 - embopress.org
We demonstrate that the cytogenetically defined translocation t (X; 18)(p11. 2; q11. 2) found
in human synovial sarcoma results in the fusion of the chromosome 18 SYT gene to either of …
in human synovial sarcoma results in the fusion of the chromosome 18 SYT gene to either of …
hTAF (II) 68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.
A Bertolotti, Y Lutz, DJ Heard, P Chambon… - The EMBO journal, 1996 - embopress.org
TFIID is the main sequence‐specific DNA‐binding component of the RNA polymerase II (Pol
II) transcriptional machinery. It is a multiprotein complex composed of the TATA‐binding …
II) transcriptional machinery. It is a multiprotein complex composed of the TATA‐binding …
Ancestry and diversity of the HMG box superfamily
The HMG box Is a novel type of DNA-blndlng domain found in a diverse group of proteins.
The HMG box superfamily comprises ao the High Mobility Group proteins HMG1 and HMG2 …
The HMG box superfamily comprises ao the High Mobility Group proteins HMG1 and HMG2 …
Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.
T Georgakopoulos, G Thireos - The EMBO journal, 1992 - embopress.org
When yeast cells are grown under conditions of amino acid limitation, transcription of amino
acid biosynthetic genes is increased through the action of the GCN4 transcriptional …
acid biosynthetic genes is increased through the action of the GCN4 transcriptional …