The World Health Organisation 2016 classification of penile carcinomas: a review and update from the International Society of Urological Pathology expert‐driven …

AL Cubilla, EF Velazquez, MB Amin, J Epstein… - …, 2018 - Wiley Online Library
The International Society of Urological Pathology (ISUP) held an expert‐driven penile
cancer conference in Boston in March 2015, which focused on the new World Health …

The molecular pathogenesis of penile carcinoma—current developments and understanding

A Emmanuel, J Nettleton, N Watkin, DM Berney - Virchows Archiv, 2019 - Springer
Penile squamous cell carcinoma is a rare malignancy with various distinct histological
subtypes, each with distinct appearances, histotypic specific associations with human …

WHO 2022 classification of penile and scrotal cancers: updates and evolution

S Menon, H Moch, DM Berney, IA Cree… - …, 2023 - Wiley Online Library
Squamous cell carcinoma (SCC) is the most common malignant tumour of the penis. The
2022 WHO classification reinforces the 2016 classification and subclassifies precursor …

What is new in the pathologic staging of penile carcinoma in the 8th edition of AJCC TNM model: rationale for changes with practical stage-by-stage category …

DF Sanchez, MJ Fernandez-Nestosa… - Advances in …, 2021 - journals.lww.com
For> 50 years the tumor, node, metastasis (TNM) classification model of malignant tumors
has been the main resource for clinicians, pathologists, radiologists and public health …

Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers V: Recommendations on …

S Canete-Portillo, EF Velazquez… - The American Journal …, 2020 - journals.lww.com
Penile cancer and its precursor lesions are morphologically and clinically heterogenous and
they can be further characterized by immunohistochemical (IHC) and molecular genetic …

Detection of variable genotypes in common human papillomavirus-associated invasive penile squamous cell carcinomas: a study of 177 human papillomavirus …

DF Sanchez, MJ Fernández-Nestosa, L Alemany… - Human Pathology, 2023 - Elsevier
Human papillomavirus (HPV) is detected in 30–50% of invasive penile carcinomas, and it is
frequently associated with basaloid and warty morphological features. Based on this …

HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV‐related penile cancer

B Medeiros‐Fonseca, VF Mestre… - The Journal of …, 2020 - Wiley Online Library
Penile cancer is an under‐studied disease that occurs more commonly in developing
countries and 30–50% of cases show high‐risk human papillomavirus (HPV) infection …

Human papillomavirus (HPV) genotypes in condylomas, intraepithelial neoplasia, and invasive carcinoma of the penis using laser capture microdissection (LCM) …

MJ Fernández-Nestosa, N Guimerà… - The American journal …, 2017 - journals.lww.com
Laser capture microdissection-polymerase chain reaction (LCM-PCR) supported by p16
INK4a was used for the first time to demonstrate human papillomavirus (HPV) DNA in …

Pathology of invasive and intraepithelial penile neoplasia

S Canete-Portillo, DF Sanchez, AL Cubilla - European Urology Focus, 2019 - Elsevier
Since 1995 it has been known that tumors harboring human papillomavirus (HPV)
preferentially show basaloid or condylomatous histological features, while HPV-negative …

Evolving insights into penile cancer pathology and the eighth edition of the AJCC TNM staging system

DF Sanchez, MJ Fernandez-Nestosa… - … Oncology: Seminars and …, 2022 - Elsevier
The majority of penile malignant tumors are squamous cell carcinomas. They are
pathologically defined as epithelial neoplasms originating in the squamous cells of the inner …