Nanoparticles overcome adaptive immune resistance and enhance immunotherapy via targeting tumor microenvironment in lung cancer

X Zhang, X Wang, L Hou, Z Xu, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is one of the common malignant cancers worldwide. Immune checkpoint
inhibitor (ICI) therapy has improved survival of lung cancer patients. However, ICI therapy …

Liquid biopsy in non-small cell lung cancer: a meta-analysis of state-of-the-art and future perspectives

S Franzi, G Seresini, P Borella, PR Raviele… - Frontiers in …, 2023 - frontiersin.org
Introduction: To date, tissue biopsy represents the gold standard for characterizing non-
small-cell lung cancer (NSCLC), however, the complex architecture of the disease has …

In-silico and in-vitro identification of triazole based compounds as potential EGFR inhibitors targeting lung cancer

S Kumar, MK Shukla, I Ali, F Abbas, R Verma… - Molecular …, 2023 - Taylor & Francis
The use of FDA-approved drugs for the therapy of lung cancer through drug repurposing is a
noteworthy approach. We retrieved all the FDA-approved triazole-based drugs from …

JAC4 inhibits EGFR-driven lung adenocarcinoma growth and metastasis through CTBP1-mediated JWA/AMPK/NEDD4L/EGFR Axis

K Ding, X Jiang, Z Wang, L Zou, J Cui, X Li… - International Journal of …, 2023 - mdpi.com
Lung adenocarcinoma (LUAD) is the most common lung cancer, with high mortality. As a
tumor-suppressor gene, JWA plays an important role in blocking pan-tumor progression …

Identification of m7G-Related miRNA Signatures Associated with Prognosis, Oxidative Stress, and Immune Landscape in Lung Adenocarcinoma

S Jiang, M Xiao, Y Shi, Y Wang, Z Xu, K Wang - Biomedicines, 2023 - mdpi.com
The role of N7-methylguanosine (m7G)-related miRNAs in lung adenocarcinoma (LUAD)
remains unclear. We used LUAD data from The Cancer Genome Atlas (TCGA) to establish a …

[HTML][HTML] Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target

R Sciarrillo, F Terrana, A Comandatore… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) poses significant challenges in terms of
prognosis and treatment. Recent research has identified splicing deregulation as a new …

Cytoplasmic Shotgun Proteomic Points to Key Proteins and Pathways in Temozolomide-Resistant Glioblastoma Multiforme

M Teraiya, O Krokhin, VC Chen… - Journal of Proteome …, 2023 - ACS Publications
Temozolomide (TMZ) is the first line of chemotherapy to treat primary brain tumors of the
type glioblastoma multiforme (GBM). TMZ resistance (TMZR) is one of the main barriers to …

[HTML][HTML] Lung Cancer Subtyping: A Short Review

F Siddique, M Shehata, M Ghazal, S Contractor… - Cancers, 2024 - mdpi.com
Simple Summary Lung cancer is the most commonly diagnosed and most lethal cancer.
Since healthcare outcomes have improved with the advent of targeted therapy, it is …

[HTML][HTML] ERS international congress 2022: Highlights from the thoracic oncology assembly

MJ Catarata, WH Van Geffen, R Banka… - ERJ Open …, 2023 - Eur Respiratory Soc
Thoracic malignancies are associated with a substantial public health burden. Lung cancer
is the leading cause of cancer-related mortality worldwide, with significant impact on …

Recent Advancements in Minimally Invasive Surgery for Early Stage Non-Small Cell Lung Cancer: A Narrative Review

JA Khan, I Albalkhi, S Garatli, M Migliore - Journal of Clinical Medicine, 2024 - mdpi.com
Introduction: Lung cancer remains a global health concern, with non-small cell lung cancer
(NSCLC) comprising the majority of cases. Early detection of lung cancer has led to an …