This review provides comprehensive information about the advances in gene therapy in the
anterior segment of the eye, including cornea, conjunctiva, lacrimal gland, and trabecular …

Vapor nanobubble-mediated photoporation has evolved into a promising physical
intracellular delivery technology. When irradiated with short but intense laser pulses …

Ocular drug delivery is an interesting field in current research. Silica nanoparticles (SiNPs)
are promising drug carriers for ophthalmic drug delivery. However, little is known about the …

Nanoneedles can target nucleic acid transfection to primary cells at tissue interfaces with
high efficiency and minimal perturbation. The corneal endothelium is an ideal target for …

Nonporous silica nanoparticles (SiNPs) are promising drug carrier platforms for intraocular
drug delivery. In this study, we investigated the safety of three different sizes of SiNPs (50 …

Introduction Hepatocellular cancer stem cells (CSCs) play crucial roles in hepatocellular
cancer initiation, development, relapse, and metastasis. Therefore, eradication of this cell …

Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic
drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study …

The delivery of macromolecules into living cells is challenging since in most cases
molecules are endocytosed and remain in the endo‐lysosomal pathway where they are …

Purpose: Silica nanoparticles (SiNPs) are promising carriers for ophthalmic drug delivery. In
this study, we investigated the effect of various sizes of nonporous SiNPs on cultured human …

When a system comprised of cells, carbon black nanoparticles, and delivery molecules is
irradiated with a laser beam, the nanoparticles can absorb and dissipate the laser-delivered …