[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
[HTML][HTML] Mitochondrial dysfunction: the hidden player in the pathogenesis of atherosclerosis?
G Ciccarelli, S Conte, G Cimmino, P Maiorano… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …
[HTML][HTML] Novel strategies in the early detection and treatment of endothelial cell-specific mitochondrial dysfunction in coronary artery disease
WE Lee, E Genetzakis, GA Figtree - Antioxidants, 2023 - mdpi.com
Although elevated cholesterol and other recognised cardiovascular risk factors are important
in the development of coronary artery disease (CAD) and heart attack, the susceptibility of …
in the development of coronary artery disease (CAD) and heart attack, the susceptibility of …
Targeting mitochondrial function in macrophages: A novel treatment strategy for atherosclerotic cardiovascular disease?
PH Becker, P Thérond, P Gaignard - Pharmacology & Therapeutics, 2023 - Elsevier
Atherosclerotic cardiovascular disease is a major cause of morbidity and mortality due to
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …
[HTML][HTML] Neuroprotective potential of mild uncoupling in mitochondria. Pros and cons
DB Zorov, NV Andrianova, VA Babenko, IB Pevzner… - Brain Sciences, 2021 - mdpi.com
There has been an explosion of interest in the use of uncouplers of oxidative
phosphorylation in mitochondria in the treatment of several pathologies, including …
phosphorylation in mitochondria in the treatment of several pathologies, including …
Mitochondrial dysfunction in the pathogenesis of endothelial dysfunction
SK Prajapat, KC Maharana, S Singh - Molecular and Cellular Biochemistry, 2023 - Springer
Cardiovascular diseases (CVDs) are a matter of concern worldwide, and mitochondrial
dysfunction is one of the major contributing factors. Vascular endothelial dysfunction has a …
dysfunction is one of the major contributing factors. Vascular endothelial dysfunction has a …
Mitochondrial proton leak in cardiac aging
Age-associated diseases are becoming progressively more prevalent, reflecting the
increased lifespan of the world's population. However, the fundamental mechanisms of …
increased lifespan of the world's population. However, the fundamental mechanisms of …
[HTML][HTML] Protective effects of 2, 4-dinitrophenol in okadaic acid-induced cellular model of Alzheimer's disease
Alzheimer's disease (AD) research started several decades ago and despite the many
efforts employed to develop new treatments or approaches to slow and/or revert disease …
efforts employed to develop new treatments or approaches to slow and/or revert disease …
[HTML][HTML] In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice
MIC Queiroz, CM Lazaro, LMB Dos Santos… - Ecotoxicology and …, 2024 - Elsevier
Heavy metal exposure leads to multiple system dysfunctions. The mechanisms are likely
multifactorial and involve inflammation and oxidative stress. The aim of this study was to …
multifactorial and involve inflammation and oxidative stress. The aim of this study was to …
The Impact of Ketone Body Metabolism on Mitochondrial Function and Cardiovascular Diseases
Y Arima - Journal of Atherosclerosis and Thrombosis, 2023 - jstage.jst.go.jp
Ketone bodies, consisting of beta-hydroxybutyrate, acetoacetate, and acetone, are
metabolic byproducts known as energy substrates during fasting. Recent advancements …
metabolic byproducts known as energy substrates during fasting. Recent advancements …