Transformation (ie genetic modification of a cell by the incorporation of exogenous DNA) is
indispensable for manipulating fungi. Here, we review the transformation methods for …

The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Fourteen Aspergillus fumigatus clinical isolates that exhibited a pattern of reduced
susceptibility to triazole drugs were analyzed. The sequences of the cyp51A gene from all …

Filamentous fungi have long been used for production of a range of valuable products; with
the advent of molecular biology, it became apparent that these fungi possess considerable …

Entomopathogenic fungi are currently being used for the control of several insect pests as
alternatives or supplements to chemical insecticides. Improvements in virulence and speed …

The genes encoding 14α-sterol demethylases (cyp51A and cyp51B) were analyzed in 12
itraconazole (ITC)-resistant and three ITC-susceptible clinical isolates of Aspergillus …

Molecular genetic manipulation of micro‐organisms requires the development of plasmid‐
mediated transformation systems that include:(i) infusion of exogenous DNA into recipient …

Reactive oxidant species produced by phagocytes have been reported as being involved in
the killing of Aspergillus fumigatus. Fungal superoxide dismutases (SODs) that detoxify …

Several pathogenic fungal organisms enter eukaryotic cells and manipulate the host cell
environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic …

In eukaryotic cells, environmental stress signals are transmitted by evolutionarily conserved
MAPKs, such as Hog1 in the budding yeast Saccharomyces cerevisiae, Spc1 in the fission …