Importance The magnitude and variability of cytokine alterations in depression are not clear.
Objective To perform an up to date meta-analysis of mean differences of immune markers in …

BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …

Background This study examines the predictive value of a novel systemic immune‐
inflammation index (SII, platelet× neutrophil/lymphocyte ratio) in coronary artery disease …

The circadian system, that is ubiquitous across species, generates∼ 24 h rhythms in
virtually all biological processes, and allows them to anticipate and adapt to the 24 h …

Epidemiological studies have documented a high incidence of diabetes in hypertensive
patients. Insulin resistance is defined as a less than expected biologic response to a given …

Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This
increased risk cannot be fully explained by classic risk factors. One of the key features of …

Background: Anxiety disorders increase risk of future cardiovascular disease (CVD) and
mortality, even after controlling for confounds including smoking, lifestyle, and …

Background The discovery of novel and highly predictive biomarkers of cardiovascular
disease (CVD) has the potential to improve risk‐stratification methods and may be …

Background and objectives: Periodontitis is a multifactorial chronic inflammatory infectious
disease in which an infection is necessary, but not sufficient, for development of the …

Obesity is a public health problem that has reached epidemic proportions with an increasing
worldwide prevalence. The global emergence of obesity increases the risk of developing …