Lactic acid for green chemical industry: recent advances in and future prospects for production technology, recovery, and applications
Lactic acid, an organic acid produced by numerous microorganisms, has many applications
in the food, chemical, pharmaceutical, and polymer industries, with novel applications being …
in the food, chemical, pharmaceutical, and polymer industries, with novel applications being …
Microbial production of lactic acid
MA Eiteman, S Ramalingam - Biotechnology letters, 2015 - Springer
Lactic acid is an important commodity chemical having a wide range of applications.
Microbial production effectively competes with chemical synthesis methods because …
Microbial production effectively competes with chemical synthesis methods because …
An efficient production of bio-succinate in a novel metabolically engineered Klebsiella oxytoca by rational metabolic engineering and evolutionary adaptation
C Phosriran, N Wong, K Jantama - Bioresource Technology, 2024 - Elsevier
Abstract Klebsiella oxytoca KC004 (ΔadhEΔpta-ackAΔldhAΔbudABΔpflB) was engineered
to enhance succinate production. The strain exhibited poor growth without succinate …
to enhance succinate production. The strain exhibited poor growth without succinate …
Enhanced 2,3-Butanediol Production by Optimizing Fermentation Conditions and Engineering Klebsiella oxytoca M1 through Overexpression of Acetoin Reductase
Microbial production of 2, 3-butanediol (2, 3-BDO) has been attracting increasing interest
because of its high value and various industrial applications. In this study, high production of …
because of its high value and various industrial applications. In this study, high production of …
Biotechnological production of enantiomerically pure d-lactic acid
S Klotz, N Kaufmann, A Kuenz, U Prüße - Applied microbiology and …, 2016 - Springer
The fermentation process of l-lactic acid is well known. Little importance was attached to d-
lactic acid, but in the past 10 years, d-lactic acid gained significantly in importance. d-Lactic …
lactic acid, but in the past 10 years, d-lactic acid gained significantly in importance. d-Lactic …
Efficient reduction of the formation of by-products and improvement of production yield of 2, 3-butanediol by a combined deletion of alcohol dehydrogenase, acetate …
K Jantama, P Polyiam, P Khunnonkwao, S Chan… - Metabolic …, 2015 - Elsevier
Klebsiella oxytoca KMS005 (∆ adhE∆ ackA-pta∆ ldhA) was metabolically engineered to
improve 2, 3-butanediol (BDO) yield. Elimination of alcohol dehydrogenase E (adhE) …
improve 2, 3-butanediol (BDO) yield. Elimination of alcohol dehydrogenase E (adhE) …
Efficient production of L-lactic acid using co-feeding strategy based on cane molasses/glucose carbon sources
Abstract l-Lactic acid is an important platform chemical, which ought to be produced under
cost control to meet its huge demand. Cane molasses, a waste from sugar manufacturing …
cost control to meet its huge demand. Cane molasses, a waste from sugar manufacturing …
Harnessing valorization potential of whey permeate for D-lactic acid production using lactic acid bacteria
Global milk production has increased by 59% since 1988, reaching 944 million tonnes in
2023. This surge has resulted in an annual by-product, whey, totalling 200 million tonnes …
2023. This surge has resulted in an annual by-product, whey, totalling 200 million tonnes …
Genome engineering of Kluyveromyces marxianus for high D-( −)-lactic acid production under low pH conditions
C Gosalawit, P Khunnonkwao, K Jantama - Applied Microbiology and …, 2023 - Springer
Saccharomyces cerevisiae is the workhorse of fermentation industry. Upon engineering for
D-lactate production by a series of gene deletions, this yeast had deficiencies in cell growth …
D-lactate production by a series of gene deletions, this yeast had deficiencies in cell growth …
Coordination of metabolic pathways: enhanced carbon conservation in 1, 3-propanediol production by coupling with optically pure lactate biosynthesis
Metabolic engineering has emerged as a powerful tool for bioproduction of both fine and
bulk chemicals. The natural coordination among different metabolic pathways contributes to …
bulk chemicals. The natural coordination among different metabolic pathways contributes to …