The extracellular matrix (ECM) is a complex assembly of hundreds of proteins forming the
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …

Glycosylation is a common post-translational modification of brain proteins including cell
surface adhesion molecules, synaptic proteins, receptors and channels, as well as …

A significant portion of mammalian proteomes is secreted to the extracellular space to fulfill
crucial roles in cell-to-cell communication. To best recapitulate the intricate and multi-faceted …

After traumatic brain injury, the brain extracellular matrix undergoes structural
rearrangement due to changes in matrix composition, activation of proteases, and …

The utilization of explosives and chemicals has resulted in a rise in blast-induced traumatic
brain injury (bTBI) in recent times. However, there is a dearth of diagnostic biomarkers and …

The role of the extracellular matrix (ECM) in Parkinson's disease (PD) is not well understood,
even though it is critical for neuronal structure and signaling. This systematic review …

Molecular omics technologies, including proteomics, have enabled the elucidation of key
signaling pathways that mediate bidirectional communication between the brain and bone …