Adaptive optics for high-resolution imaging
Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …
Regenerative and restorative medicine for eye disease
Causes of blindness differ across the globe; in higher-income countries, most blindness
results from the degeneration of specific classes of cells in the retina, including retinal …
results from the degeneration of specific classes of cells in the retina, including retinal …
[HTML][HTML] Adaptive optics imaging of the human retina
Adaptive Optics (AO) retinal imaging has provided revolutionary tools to scientists and
clinicians for studying retinal structure and function in the living eye. From animal models to …
clinicians for studying retinal structure and function in the living eye. From animal models to …
Inherited retinal degenerations: current landscape and knowledge gaps
Inherited retinal degenerations (IRDs) represent a diverse group of progressive, visually
debilitating diseases that can lead to blindness in which mutations in genes that are critical …
debilitating diseases that can lead to blindness in which mutations in genes that are critical …
Imaging and quantifying ganglion cells and other transparent neurons in the living human retina
Ganglion cells (GCs) are fundamental to retinal neural circuitry, processing photoreceptor
signals for transmission to the brain via their axons. However, much remains unknown about …
signals for transmission to the brain via their axons. However, much remains unknown about …
Activated retinal pigment epithelium, an optical coherence tomography biomarker for progression in age-related macular degeneration
CA Curcio, EC Zanzottera, T Ach… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To summarize and contextualize recent histology and clinical imaging publications
on retinal pigment epithelium (RPE) fate in advanced age-related macular degeneration …
on retinal pigment epithelium (RPE) fate in advanced age-related macular degeneration …
Evolution of adaptive optics retinal imaging
This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …
Twenty-five years of clinical applications using adaptive optics ophthalmoscopy
JIW Morgan, TYP Chui, K Grieve - Biomedical Optics Express, 2022 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
JR Soucy, EA Aguzzi, J Cho, MJ Gilhooley… - Molecular …, 2023 - Springer
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …
irreversible vision loss due to the mammalian central nervous system's limited regenerative …
[HTML][HTML] Endpoints for clinical trials in ophthalmology
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …
ophthalmology has increased. Visual acuity has for a long time been considered the gold …