Exosome‐mediated effects and applications in inflammatory bowel disease

DKW Ocansey, L Zhang, Y Wang, Y Yan… - Biological …, 2020 - Wiley Online Library
Gut mucosal barriers, including chemical and physical barriers, spatially separate the gut
microbiota from the host immune system to prevent unwanted immune responses that could …

Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer

G Patel, TG Agnihotri, M Gitte, T Shinde, SS Gomte… - Cellular Oncology, 2023 - Springer
Background Exosomes are nanosized bio vesicles formed when multivesicular bodies and
the plasma membrane merge and discharge into bodily fluids. They are well recognized for …

A sensitive aptasensor based on a hemin/G‐Quadruplex‐assisted signal amplification strategy for electrochemical detection of gastric cancer exosomes

R Huang, L He, Y Xia, H Xu, C Liu, H Xie, S Wang… - Small, 2019 - Wiley Online Library
Emerging evidence indicates that exosomes derived from gastric cancer cells enhance
tumor migration and invasion through the modulation of the tumor microenvironment …

CD44/CD44v6 a reliable companion in cancer-initiating cell maintenance and tumor progression

Z Wang, K Zhao, T Hackert, M Zöller - Frontiers in cell and …, 2018 - frontiersin.org
Metastasis is the leading cause of cancer death, tumor progression proceeding through
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …

Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway

S Wang, X Su, M Xu, X Xiao, X Li, H Li… - Stem cell research & …, 2019 - Springer
Objective Although adipocytes are the most abundant stromal cell component in breast
cancer tissues, their interaction with breast cancer cells has been less investigated …

Tumor-derived exosomal miR-619-5p promotes tumor angiogenesis and metastasis through the inhibition of RCAN1. 4

DH Kim, S Park, HR Kim, YJ Choi, SY Kim, KJ Sung… - Cancer letters, 2020 - Elsevier
Tumor-derived exosomes (TEXs) contain enriched miRNAs that act as novel non-invasive
biomarkers for cancer diagnosis and play a role in cancer progression. We investigated the …

[HTML][HTML] Serum exosomal miR-122 as a potential diagnostic and prognostic biomarker of colorectal cancer with liver metastasis

L Sun, X Liu, B Pan, X Hu, Y Zhu, Y Su, Z Guo… - Journal of …, 2020 - ncbi.nlm.nih.gov
Background: Liver is the most common site for metastatic spread of CRC at the time of
diagnosis which leads to high mortality. This study aimed to identify novel circulating …

Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K …

L Qiu, J Wang, M Chen, F Chen… - … journal of molecular …, 2020 - spandidos-publications.com
The carrier role of exosomes from human umbilical cord mesenchymal stem cells
(hUCMSCs) containing microRNAs (miRNAs) has been implicated in gene and drug …

Extracellular vesicles containing PD-L1 contribute to CD8+ T-cell immune suppression and predict poor outcomes in small cell lung cancer

X Dou, Y Hua, Z Chen, F Chao… - Clinical and Experimental …, 2022 - academic.oup.com
Abstract Programmed death ligand-1 (PD-L1) is expressed on the surface of tumor cells and
binds to programmed cell death protein-1 (PD1) on the surface of T cells, leading to cancer …

Exosomes regulate the transformation of cancer cells in cancer stem cell homeostasis

J Xu, K Liao, W Zhou - Stem cells international, 2018 - Wiley Online Library
In different biological model systems, exosomes are considered mediators of cell‐cell
communication between different cell populations. Exosomes, as extracellular vesicles …