PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …

RNA silencing refers to gene silencing pathways mediated by small non-coding RNAs,
including microRNAs. Piwi-interacting RNAs (piRNAs) constitute the largest class of small …

Abstract The PIWI‐interacting RNA (piRNA) pathway acts as a self‐defense mechanism
against transposons to maintain germline genome integrity. Failures in the piRNA pathway …

PIWI-interacting RNAs (piRNAs) guide transposable element repression in animal germ
lines. In Drosophila, piRNAs are produced from heterochromatic loci, called piRNA clusters …

The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to
protect animal germ cells. In Drosophila, Panoramix enforces transcriptional silencing by …

Primary ovarian insufficiency (POI) affects 1% of women and carries significant medical and
psychosocial sequelae. Approximately 10% of POI has a defined genetic cause, with most …

The maintenance of chromosome ends in Drosophila is an exceptional phenomenon
because it relies on the transposition of specialized retrotransposons rather than on the …

Summary dsRNA sensing triggers antiviral responses against RNA and DNA viruses in
diverse eukaryotes. In Drosophila, Invertebrate iridescent virus 6 (IIV-6), a large DNA virus …

piRNAs are small non-coding RNAs that guide the silencing of transposons and other
targets in animal gonads. In Drosophila female germline, many piRNA source loci dubbed …

Transposable elements (TEs) are mobile genetic parasites that can exponentially increase
their genomic abundance through self-propagation. Classic theoretical papers highlighted …