Review The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge

K Tomczak, P Czerwińska… - Contemporary Oncology …, 2015 - termedia.pl
The Cancer Genome Atlas (TCGA) is a public funded project that aims to catalogue and
discover major cancer-causing genomic alterations to create a comprehensive “atlas” of …

Robust nucleus/cell detection and segmentation in digital pathology and microscopy images: a comprehensive review

F Xing, L Yang - IEEE reviews in biomedical engineering, 2016 - ieeexplore.ieee.org
Digital pathology and microscopy image analysis is widely used for comprehensive studies
of cell morphology or tissue structure. Manual assessment is labor intensive and prone to …

A multi-organ nucleus segmentation challenge

N Kumar, R Verma, D Anand, Y Zhou… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Generalized nucleus segmentation techniques can contribute greatly to reducing the time to
develop and validate visual biomarkers for new digital pathology datasets. We summarize …

A dataset and a technique for generalized nuclear segmentation for computational pathology

N Kumar, R Verma, S Sharma… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Nuclear segmentation in digital microscopic tissue images can enable extraction of high-
quality features for nuclear morphometrics and other analysis in computational pathology …

MoNuSAC2020: A multi-organ nuclei segmentation and classification challenge

R Verma, N Kumar, A Patil, NC Kurian… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Detecting various types of cells in and around the tumor matrix holds a special significance
in characterizing the tumor micro-environment for cancer prognostication and research …

Stacked sparse autoencoder (SSAE) for nuclei detection on breast cancer histopathology images

J Xu, L Xiang, Q Liu, H Gilmore, J Wu… - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Automated nuclear detection is a critical step for a number of computer assisted pathology
related image analysis algorithms such as for automated grading of breast cancer tissue …

Pannuke: an open pan-cancer histology dataset for nuclei instance segmentation and classification

J Gamper, N Alemi Koohbanani, K Benet… - Digital Pathology: 15th …, 2019 - Springer
In this work we present an experimental setup to semi automatically obtain exhaustive nuclei
labels across 19 different tissue types, and therefore construct a large pan-cancer dataset for …

An automatic learning-based framework for robust nucleus segmentation

F Xing, Y Xie, L Yang - IEEE transactions on medical imaging, 2015 - ieeexplore.ieee.org
Computer-aided image analysis of histopathology specimens could potentially provide
support for early detection and improved characterization of diseases such as brain tumor …

Accurate segmentation of cervical cytoplasm and nuclei based on multiscale convolutional network and graph partitioning

Y Song, L Zhang, S Chen, D Ni, B Lei… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
In this paper, a multiscale convolutional network (MSCN) and graph-partitioning-based
method is proposed for accurate segmentation of cervical cytoplasm and nuclei. Specifically …

The digital slide archive: a software platform for management, integration, and analysis of histology for cancer research

DA Gutman, M Khalilia, S Lee, M Nalisnik, Z Mullen… - Cancer research, 2017 - AACR
Tissue-based cancer studies can generate large amounts of histology data in the form of
glass slides. These slides contain important diagnostic, prognostic, and biological …