The distributions of HLA‐A, HLA‐B, HLA‐C, HLA‐DRB1 and HLA‐DQB1 allele and haplotype at high‐resolution level in Zhejiang Han population of China

N Chen, W Wang, F Wang, L Dong… - International journal …, 2019 - Wiley Online Library
The distributions of HLA allele and haplotype are variable in different ethnic populations and
the data for some populations have been published. However, the data on HLA‐C and HLA …

[HTML][HTML] Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population

MHC Yu, MCY Chan, CCY Chung, AWT Li… - PLoS …, 2021 - journals.plos.org
Preemptive pharmacogenetic testing has the potential to improve drug dosing by providing
point-of-care patient genotype information. Nonetheless, its implementation in the Chinese …

[HTML][HTML] An original Eurasian haplotype, HLA-DRB1* 14: 54-DQB1* 05: 03, influences the susceptibility to idiopathic achalasia

J Furuzawa-Carballeda, J Zuñiga… - PLoS …, 2018 - journals.plos.org
Idiopathic achalasia is a relatively infrequent esophageal motor disorder for which major
histocompatibility complex (MHC) genes are well-identified risk factors. However, no …

HLA-B* 58: 01 screening to prevent allopurinol-induced severe cutaneous adverse reactions in Chinese patients with chronic kidney disease

CSM Wong, CK Yeung, CY Chan, DYH Yap… - Archives of …, 2022 - Springer
Human leukocyte antigen (HLA)-B* 58: 01 allele is a significant risk factor for allopurinol-
induced severe cutaneous adverse reactions (SCARs) which is potentially fatal. In some …

[HTML][HTML] Identification of 8-digit HLA-A,-B,-C, and-DRB1 allele and haplotype frequencies in Koreans using the One Lambda AllType Next-Generation Sequencing Kit

W Choe, JD Chae, JJ Yang… - Annals of …, 2021 - synapse.koreamed.org
Background Recent studies have successfully implemented next-generation sequencing
(NGS) in HLA typing. We performed HLA NGS in a Korean population to estimate HLA-A,-B …

HLA‐B* 15: 11 status and carbamazepine‐induced severe cutaneous adverse drug reactions in HLA‐B* 15: 02 negative Chinese

CSM Wong, DYH Yap, P Ip, WHS Wong, GT Chua… - 2022 - Wiley Online Library
Abstract Background HLA‐B* 15: 11 is associated with carbamazepine (CBZ)‐induced
severe cutaneous adverse drug reactions (SCARs) in Japanese and some Asian …

High resolution allele genotyping and haplotype frequencies for NGS based HLA 11 loci of 5266 Hong Kong Chinese bone marrow donors

J Kwok, WH Tang, WK Chu, YS Chan, Z Liu, W Yang… - Human Immunology, 2020 - Elsevier
Next-generation sequencing (NGS) at the HLA-A,-B,-C,-DRB1,-DRB3/4/5,-DQA1,-DQB1,-
DPA1, and-DPB1 loci was performed on 5,266 southern Chinese unrelated donors of the …

[HTML][HTML] The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2

J Zhu, J Kim, X Xiao, Y Wang, D Luo, S Jiang, R Chen… - BioRxiv, 2020 - ncbi.nlm.nih.gov
The outbreak of the 2019 Novel Coronavirus (SARS-CoV-2) rapidly spread from Wuhan,
China to more than 150 countries, areas, or territories, causing staggering numbers of …

ABO‐adjusted cPRA metric for kidney allocation in an Asian‐predominant population

KM Lau, PWK Chu, LWM Tang, BPY Chen… - HLA, 2024 - Wiley Online Library
Recent studies showed that ABO‐adjusted calculated panel reactive antibody (ABO‐cPRA)
may better reflect the histocompatibility level in a multi‐ethnic population, but such data in …

A simplified method of calculating cPRA for kidney allocation application in Hong Kong: a retrospective study

YP Chan, MWK Wong, LWM Tang, M Guo… - Transplant …, 2017 - Wiley Online Library
Calculated panel reactive antibody (cPRA) represents possibility of encountering an
incompatible donor for organ transplant candidates and has gradually replaced traditional …