[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
Approaches for enhancing oral bioavailability of peptides and proteins
J Renukuntla, AD Vadlapudi, A Patel… - International journal of …, 2013 - Elsevier
Oral delivery of peptide and protein drugs faces immense challenge partially due to the
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …
[HTML][HTML] A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives
In the modern world, a number of therapeutic proteins such as vaccines, antigens, and
hormones are being developed utilizing different sophisticated biotechnological techniques …
hormones are being developed utilizing different sophisticated biotechnological techniques …
Novel delivery approaches for cancer therapeutics
AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
Currently, a majority of cancer treatment strategies are based on the removal of tumor mass
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …
Novel strategies for anterior segment ocular drug delivery
K Cholkar, SP Patel, AD Vadlapudi… - Journal of ocular …, 2013 - liebertpub.com
Research advancements in pharmaceutical sciences have led to the development of new
strategies in drug delivery to anterior segment. Designing a new delivery system that can …
strategies in drug delivery to anterior segment. Designing a new delivery system that can …
Transporter-mediated drug delivery
G Gyimesi, MA Hediger - Molecules, 2023 - mdpi.com
Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …
Solid lipid matrix mediated nanoarchitectonics for improved oral bioavailability of drugs
S Banerjee, J Pillai - Expert opinion on drug metabolism & …, 2019 - Taylor & Francis
Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the
best features of ideal drug carriers necessary for improving the oral absorption and …
best features of ideal drug carriers necessary for improving the oral absorption and …
Physicochemical characterization techniques for solid lipid nanoparticles: principles and limitations
Solid lipid nanoparticles (SLNs) are gaining importance due to numerous advantages they
offer as a drug delivery system. SLN incorporate poorly soluble drugs, proteins, biologicals …
offer as a drug delivery system. SLN incorporate poorly soluble drugs, proteins, biologicals …
Nano lipid-drug conjugate: An integrated review
Abstract Lipid-drug conjugates (LDC), which may also be addressed as lipoidal prodrug,
have the therapeutic actives chemically bound to a lipid moiety like fatty acids or …
have the therapeutic actives chemically bound to a lipid moiety like fatty acids or …
Ocular drug delivery
B Yavuz, UB Kompella - Pharmacologic Therapy of Ocular Disease, 2017 - Springer
Although the eye is an accessible organ for direct drug application, ocular drug delivery
remains a major challenge due to multiple barriers within the eye. Key barriers include static …
remains a major challenge due to multiple barriers within the eye. Key barriers include static …