The progress in understanding and treatment of diabetic retinopathy
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …
remains a leading cause of vision loss globally. Its aetiology and pathology have been …
Molecular pathogenesis of retinal and choroidal vascular diseases
PA Campochiaro - Progress in retinal and eye research, 2015 - Elsevier
There are two major types of ocular neovascularization that affect the retina, retinal
neovascularization (NV) and subretinal or choroidal NV. Retinal NV occurs in a group of …
neovascularization (NV) and subretinal or choroidal NV. Retinal NV occurs in a group of …
Intravitreal aflibercept for diabetic macular edema
JF Korobelnik, DV Do, U Schmidt-Erfurth, DS Boyer… - Ophthalmology, 2014 - Elsevier
Purpose A head-to-head comparison was performed between vascular endothelial growth
factor blockade and laser for treatment of diabetic macular edema (DME). Design Two …
factor blockade and laser for treatment of diabetic macular edema (DME). Design Two …
[HTML][HTML] Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials: RISE and RIDE
DM Brown, QD Nguyen, DM Marcus, DS Boyer, S Patel… - Ophthalmology, 2013 - Elsevier
Purpose To report 36-month outcomes of RIDE (NCT00473382) and RISE (NCT00473330),
trials of ranibizumab in diabetic macular edema (DME). Design Phase III, randomized …
trials of ranibizumab in diabetic macular edema (DME). Design Phase III, randomized …
Ranibizumab for diabetic macular edema: results from 2 phase III randomized trials: RISE and RIDE
QD Nguyen, DM Brown, DM Marcus, DS Boyer, S Patel… - Ophthalmology, 2012 - Elsevier
PURPOSE: To evaluate the efficacy and safety of intravitreal ranibizumab in diabetic
macular edema (DME) patients. DESIGN: Two parallel, methodologically identical, phase III …
macular edema (DME) patients. DESIGN: Two parallel, methodologically identical, phase III …
[HTML][HTML] Ocular complications of diabetes mellitus
N Sayin, N Kara, G Pekel - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a important health problem that induces ernestful complications
and it causes significant morbidity owing to specific microvascular complications such as …
and it causes significant morbidity owing to specific microvascular complications such as …
Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
OBJECTIVE: Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with
focal/grid laser compared with focal/grid laser alone for treatment of diabetic macular edema …
focal/grid laser compared with focal/grid laser alone for treatment of diabetic macular edema …
Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study) A 12-month, randomized, controlled, double-masked, multicenter phase II study
P Massin, F Bandello, JG Garweg, LL Hansen… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE The expression of vascular endothelial growth factor (VEGF) is elevated in
diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants …
diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants …
Anti‐vascular endothelial growth factor for diabetic macular oedema
G Virgili, M Parravano, F Menchini… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Diabetic macular oedema (DMO) is a common complication of diabetic
retinopathy. Although grid or focal laser photocoagulation has been shown to reduce the risk …
retinopathy. Although grid or focal laser photocoagulation has been shown to reduce the risk …
Clinical pharmacology of intravitreal anti-VEGF drugs
Clinical efficacy of intravitreal anti-VEGF drugs has been widely demonstrated in several
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …