Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …

Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

Keratins make up the largest subgroup of intermediate filament proteins and represent the
most abundant proteins in epithelial cells. They exist as highly dynamic networks of …

Small heat shock proteins (sHSPs) are present in all kingdoms of life and play fundamental
roles in cell biology. sHSPs are key components of the cellular protein quality control …

Abstract Charcot-Marie-Tooth disease (CMT) is the most common inherited neuromuscular
disease and is characterized by considerable clinical and genetic heterogeneity. We …

Heat shock proteins (HSP) are a subset of the molecular chaperones, best known for their
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …

Small heat shock proteins (sHSPs) associate with nuclei, cytoskeleton and membranes, and
as molecular chaperones they bind partially denatured proteins, thereby preventing …

Heat shock proteins (Hsps) comprise several different families of proteins that are induced in
response to a wide variety of physiological and environmental insults. One such protein …

Publisher Summary The goal of this chapter is to clarify the diversity within the heat shock
proteins (sHsps) family and to describe evidence indicating that sHsps have many different …

Intermediate filament (IF) proteins and heat shock proteins (HSPs) are large multimember
families that share several features, including protein abundance, significant upregulation in …