Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2021 - pubs.rsc.org
This review covers the literature published in 2019 for marine natural products (MNPs), with
719 citations (701 for the period January to December 2019) referring to compounds …

[HTML][HTML] The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987–2020)

Y Hai, MY Wei, CY Wang, YC Gu, CL Shao - Marine Life Science & …, 2021 - Springer
Natural products derived from marine microorganisms have received great attention as a
potential resource of new compound entities for drug discovery. The unique marine …

[HTML][HTML] Insight into chemical basis of traditional Chinese medicine based on the state-of-the-art techniques of liquid chromatography− mass spectrometry

Y Yu, C Yao, D Guo - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Traditional Chinese medicine (TCM) has been an indispensable source of drugs for curing
various human diseases. However, the inherent chemical diversity and complexity of TCM …

[HTML][HTML] Global analysis of the biosynthetic chemical space of marine prokaryotes

B Wei, GA Hu, ZY Zhou, WC Yu, AQ Du, CL Yang… - Microbiome, 2023 - Springer
Background Marine prokaryotes are a rich source of novel bioactive secondary metabolites
for drug discovery. Recent genome mining studies have revealed their great potential to bio …

Co-culture: stimulate the metabolic potential and explore the molecular diversity of natural products from microorganisms

XY Peng, JT Wu, CL Shao, ZY Li, M Chen… - Marine life science & …, 2021 - Springer
Microbial secondary metabolites have long been considered as potential sources of lead
compounds for medicinal use due to their rich chemical diversity and extensive biological …

[HTML][HTML] Peptides from marine-derived Fungi: chemistry and biological activities

S Hafez Ghoran, F Taktaz, E Sousa, C Fernandes… - Marine Drugs, 2023 - mdpi.com
Marine natural products are well-recognized as potential resources to fill the pipeline of drug
leads to enter the pharmaceutical industry. In this circumstance, marine-derived fungi are …

[HTML][HTML] Metabolites from marine invertebrates and their symbiotic microorganisms: Molecular diversity discovery, mining, and application

L Liu, YY Zheng, CL Shao, CY Wang - Marine Life Science & Technology, 2019 - Springer
Metabolites from marine organisms have proven to be a rich source for the discovery of
multiple potent bioactive molecules with diverse structures. In recent years, we initiated a …

Targeted isolation of asperheptatides from a coral-derived fungus using LC-MS/MS-based molecular networking and antitubercular activities of modified cinnamate …

R Chao, XM Hou, WF Xu, Y Hai, MY Wei… - Journal of Natural …, 2020 - ACS Publications
Under the guidance of MS/MS-based molecular networking, four new cycloheptapeptides,
namely, asperheptatides A–D (1–4), were isolated together with three known analogues …

[HTML][HTML] Secondary metabolites from coral-associated fungi: Source, chemistry and bioactivities

Y Chen, X Pang, Y He, X Lin, X Zhou, Y Liu, B Yang - Journal of Fungi, 2022 - mdpi.com
Our study of the secondary metabolites of coral-associated fungi produced a valuable and
extra-large chemical database. Many of them exhibit strong biological activity and can be …

Sulfur-containing marine natural products as leads for drug discovery and development

FW Guo, Q Zhang, YC Gu, CL Shao - Current Opinion in Chemical Biology, 2023 - Elsevier
Among the large series of marine natural products (MNPs), sulfur-containing MNPs have
emerged as potential therapeutic agents for the treatment of a range of diseases. Herein, we …