The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

AO Ceceli, CW Bradberry, RZ Goldstein - Neuropsychopharmacology, 2022 - nature.com
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Resting state functional connectivity in addiction: Lessons learned and a road ahead

MT Sutherland, MJ McHugh, V Pariyadath, EA Stein - Neuroimage, 2012 - Elsevier
Despite intensive scientific investigation and public health imperatives, drug addiction
treatment outcomes have not significantly improved in more than 50years. Non-invasive …

Brain structure and functional connectivity associated with pornography consumption: the brain on porn

S Kühn, J Gallinat - JAMA psychiatry, 2014 - jamanetwork.com
Importance Since pornography appeared on the Internet, the accessibility, affordability, and
anonymity of consuming visual sexual stimuli have increased and attracted millions of users …

Revisiting the role of the insula in addiction

V Droutman, SJ Read, A Bechara - Trends in cognitive sciences, 2015 - cell.com
Brain lesions that damage the insular cortex (IC) interrupt addictive behaviors, suggesting
that drug addiction sensitizes the insula. However, neuroimaging studies seem to lead to an …

[HTML][HTML] Meta-analysis of structural brain abnormalities associated with stimulant drug dependence and neuroimaging of addiction vulnerability and resilience

KD Ersche, GB Williams, TW Robbins… - Current opinion in …, 2013 - Elsevier
Since the first study in stimulant-dependent individuals using structural MRI was published
fifteen years ago, much evidence has accumulated on brain abnormalities associated with …

[HTML][HTML] Gray and white matter morphology in substance use disorders: a neuroimaging systematic review and meta-analysis

V Pando-Naude, S Toxto, S Fernandez-Lozano… - Translational …, 2021 - nature.com
Substance use disorders (SUDs) are characterized by a compulsion to seek and consume
one or more substances of abuse, with a perceived loss of control and a negative emotional …

Neuropathology of substance use disorders

JL Cadet, V Bisagno, CM Milroy - Acta neuropathologica, 2014 - Springer
Addictions to licit and illicit drugs are chronic relapsing brain disorders that affect circuits that
regulate reward, motivation, memory, and decision-making. Drug-induced pathological …

The cerebellum and addiction: insights gained from neuroimaging research

EA Moulton, I Elman, LR Becerra… - Addiction …, 2014 - Wiley Online Library
Although cerebellar alterations have been consistently noted in the addiction literature, the
pathophysiology of this link remains unclear. The cerebellum is commonly classified as a …

Trait impulsivity and prefrontal gray matter reductions in cocaine dependent individuals

L Moreno-López, A Catena… - Drug and alcohol …, 2012 - Elsevier
BACKGROUND: Impulsivity is thought to play a key role in cocaine addiction onset and
progression; therefore, we hypothesized that different facets of impulsive personality may be …

Excess social media use in normal populations is associated with amygdala-striatal but not with prefrontal morphology

Q He, O Turel, D Brevers, A Bechara - Psychiatry Research: Neuroimaging, 2017 - Elsevier
This study aims to investigate the gray matter volume (GMV) of key neural systems possibly
associated with Excess Social Media Use (ESMU) in the general user population. It employs …