Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy

S Hossain, Z Urbi, H Karuniawati, RB Mohiuddin… - Life, 2021 - mdpi.com
Infectious disease (ID) is one of the top-most serious threats to human health globally,
further aggravated by antimicrobial resistance and lack of novel immunization options …

A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug Discovery

A Intharuksa, W Arunotayanun, W Yooin, P Sirisa-Ard - Molecules, 2022 - mdpi.com
The COVID-19 pandemic has intensively disrupted global health, economics, and well-
being. Andrographis paniculata (Burm. f.) Nees has been used as a complementary …

Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches

B Zeng, A Wei, Q Zhou, M Yuan, K Lei… - Phytotherapy …, 2022 - Wiley Online Library
Abstract Andrographis paniculata (Burm. f.) Wall. ex Nees, a renowned herb medicine in
China, is broadly utilized in traditional Chinese medicine (TCM) for the treatment of cold and …

Andrographolide and its derivatives: Current achievements and future perspectives

H Zhang, S Li, Y Si, H Xu - European Journal of Medicinal Chemistry, 2021 - Elsevier
Natural product andrographolide isolated from the plant Andrographis paniculata shows a
plethora of biological activities, including anti-tumor, anti-bacterial, anti-inflammation, anti …

Improving ligand‐ranking of AutoDock Vina by changing the empirical parameters

TNH Pham, TH Nguyen, NM Tam… - Journal of …, 2022 - Wiley Online Library
Abstract AutoDock Vina (Vina) achieved a very high docking‐success rate,, but give a rather
low correlation coefficient,, for binding affinity with respect to experiments. This low …

Therapeutic and palliative role of a Unani herbal decoction in COVID-19 and similar respiratory viral illnesses: Phytochemical & pharmacological perspective

M Fazil, S Nikhat - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Outbreaks of respiratory viral infections like Severe Acute
Respiratory Syndrome, Middle-East Respiratory Syndrome, and Coronavirus Disease-2019 …

Integration of system biology tools to investigate huperzine A as an anti-Alzheimer agent

P Khanal, F Zargari, BF Far, D Kumar… - Frontiers in …, 2021 - frontiersin.org
Aim: The present study aimed to investigate huperzine A as an anti-Alzheimer agent based
on the principle that a single compound can regulate multiple proteins and associated …

A computational approach identified andrographolide as a potential drug for suppressing COVID-19-induced cytokine storm

M Rehan, F Ahmed, SM Howladar, MY Refai… - Frontiers in …, 2021 - frontiersin.org
Background The newly identified betacoronavirus SARS-CoV-2 is the causative pathogen of
the coronavirus disease of 2019 (COVID-19) that killed more than 3.5 million people till now …

A comprehensive review on disposition kinetics and dosage of oral administration of Andrographis paniculata, an alternative herbal medicine, in co-treatment of …

P Songvut, T Suriyo, D Panomvana… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a present global health crisis that is driving the
investigation of alternative phytomedicines for antiviral purposes. The evidence suggests …

Andrographolide: A herbal-chemosynthetic approach for enhancing immunity, combating viral infections, and its implication on human health

A Mishra, HA Shaik, RK Sinha, BR Shah - Molecules, 2021 - mdpi.com
Plants consistently synthesize and accumulate medically valuable secondary metabolites
which can be isolated and clinically tested under in vitro conditions. An advancement with …