Type 2 diabetes mellitus and cardiovascular disease: genetic and epigenetic links

S De Rosa, B Arcidiacono, E Chiefari… - Frontiers in …, 2018 - frontiersin.org
Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …

The potential role of platelet-related microRNAs in the development of cardiovascular events in high-risk populations, including diabetic patients: a review

J Pordzik, K Pisarz, S De Rosa, AD Jones… - Frontiers in …, 2018 - frontiersin.org
Platelet activation plays a pivotal role in the development and progression of
atherosclerosis, which often leads to potentially fatal ischemic events at later stages of the …

MiR-223-3p in cardiovascular diseases: a biomarker and potential therapeutic target

MW Zhang, YJ Shen, J Shi, JG Yu - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Cardiovascular diseases, involving vasculopathy, cardiac dysfunction, or circulatory
disturbance, have become the major cause of death globally and brought heavy social …

Hyperglycaemia suppresses microRNA expression in platelets to increase P2RY12 and SELP levels in type 2 diabetes mellitus

Z Fejes, S Póliska, Z Czimmerer… - Thrombosis and …, 2017 - thieme-connect.com
Megakaryocyte (MK)-derived miRNAs have been detected in platelets. Here, we analysed
the expression of platelet and circulating miR-223, miR-26b, miR-126 and miR-140 that …

The clinical significance of platelet microparticle-associated microRNAs

P Provost - Clinical Chemistry and Laboratory Medicine (CCLM), 2017 - degruyter.com
Circulating blood platelets play a central role in the maintenance of hemostasis. They
adhere to subendothelial extracellular matrix proteins that become exposed upon vessel …

Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease

AM Sheikh, HY Small, G Currie, C Delles - PloS one, 2016 - journals.plos.org
Background Pre-eclampsia (PE) is a complex, multi-systemic condition of pregnancy which
greatly impacts maternal and perinatal morbidity and mortality. MicroRNAs (miRs) are …

[HTML][HTML] MicroRNAs or long noncoding RNAs in diagnosis and prognosis of coronary artery disease

Y Zhang, L Zhang, Y Wang, H Ding, S Xue, H Qi… - Aging and …, 2019 - ncbi.nlm.nih.gov
Coronary artery disease (CAD) is the result of atherosclerotic plaque development in the
wall of the coronary arteries. The underlying mechanism involves atherosclerosis of the …

The function and regulation of platelet P2Y12 receptor

X Li, G Zhang, X Cao - Cardiovascular drugs and therapy, 2023 - Springer
In addition to the key role in hemostasis and thrombosis, platelets have also been wildly
acknowledged as immune regulatory cells and involving in the pathogenesis of …

Platelet internalization mediates ferroptosis in myocardial infarction

S Miao, Q Zhang, W Ding, B Hou, Z Su… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Myocardial cell death is the hallmark of myocardial infarction. In the process of
myocardial injury, platelets contribute to the pathogenesis by triggering intense inflammatory …

Modulation of circulating microRNAs levels during the switch from clopidogrel to ticagrelor

A Carino, S De Rosa, S Sorrentino… - BioMed research …, 2016 - Wiley Online Library
Background. Circulating microRNAs are appealing biomarkers to monitor several processes
underlying cardiovascular diseases. Platelets are a major source for circulating microRNAs …