Owing to their water‐rich structures, which are similar to those of biological tissues,
hydrogels have long been regarded as promising scaffolds for artificial tissues and organs …

The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

Creating mechanically strong macroporous hydrogels with anisotropic properties as
observed in many biological tissues is a major challenge in the gel science. Here we …

This study revealed the distinguished changes of preferential orientation of collagen and
apatite and Young's modulus in two different types of osteoporotic bones compared with the …

We report a microfluidic approach to impart alignment in ECM components in 3D hydrogels
by continuously applying fluid flow across the bulk gel during the gelation process. The …

In our previous work, we have shown that “electrostatic forces”, when generated
anisotropically in aqueous media by 2D electrolytes upon cofacial orientation, enable the …

Osteopetrotic bone shows dissociation between bone mineral density (BMD) and bone
strength. In this study, volumetric BMD; preferential orientation of the extracellular matrix …

BACKGROUND CONTEXT Therapeutic devices for spinal disorders, such as spinal fusion
cages, must be able to facilitate the maintenance and rapid recovery of spinal function …

Combination therapy with bisphosphonates and vitamin D 3 analogs has been frequently
used for the treatment of osteoporosis. However, its effects on bone anisotropies, such as …

Hypothesis Liquid crystal hydroglass (LCH) is a biphasic soft material with flow
programmable anisotropy that forms via phase separation in suspensions of charged …