Background Chronic exercise training has been shown be to positively associated with
executive function (EF) in older adults. However, whether the exercise training effect on EF …

Sex hormones act throughout the entire brain of both males and females via both genomic
and nongenomic receptors. Sex hormones can act through many cellular and molecular …

Exercise is a non-pharmacological strategy to mitigate the deleterious effects of aging on
brain health. However, a large amount of variation exists in its efficacy. Sex of participants …

Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …

Despite the practical implication of mild exercise, little is known about its influence on
executive function and its neural substrates. To address these issues, the present study …

Key points Aerobic exercise, such as running, enhances adult hippocampal neurogenesis
(AHN) in rodents. Little is known about the effects of high‐intensity interval training (HIT) or …

Contrary to popular belief, sex hormones act throughout the entire brain of both males and
females via both genomic and nongenomic receptors. Many neural and behavioral functions …

Physical exercise has beneficial effects on neurocognitive function, including hippocampus-
dependent episodic memory. Exercise intensity level can be assessed according to whether …

No medications are proven to slow the progression of Parkinson disease (PD). Of special
concern with longer-standing PD is cognitive decline, as well as motor symptoms …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …