Unsupervised multi-omics data integration methods: a comprehensive review
N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …
[HTML][HTML] A survey on single and multi omics data mining methods in cancer data classification
Data analytics is routinely used to support biomedical research in all areas, with particular
focus on the most relevant clinical conditions, such as cancer. Bioinformatics approaches, in …
focus on the most relevant clinical conditions, such as cancer. Bioinformatics approaches, in …
Integrative survival analysis of breast cancer with gene expression and DNA methylation data
I Bichindaritz, G Liu, C Bartlett - Bioinformatics, 2021 - academic.oup.com
Motivation Integrative multi-feature fusion analysis on biomedical data has gained much
attention recently. In breast cancer, existing studies have demonstrated that combining …
attention recently. In breast cancer, existing studies have demonstrated that combining …
Autoencoded DNA methylation data to predict breast cancer recurrence: Machine learning models and gene-weight significance
L Macías-García, M Martinez-Ballesteros… - Artificial Intelligence in …, 2020 - Elsevier
Breast cancer is the most frequent cancer in women and the second most frequent overall
after lung cancer. Although the 5-year survival rate of breast cancer is relatively high …
after lung cancer. Although the 5-year survival rate of breast cancer is relatively high …
Robust pathway-based multi-omics data integration using directed random walks for survival prediction in multiple cancer studies
Background Integrating the rich information from multi-omics data has been a popular
approach to survival prediction and bio-marker identification for several cancer studies. To …
approach to survival prediction and bio-marker identification for several cancer studies. To …
IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma
C Liu, W Zhang, X Zhou, L Liu - Frontiers in Immunology, 2022 - frontiersin.org
Backgrounds IMPDH1, a rate-limiting enzyme in de novos synthesis of guanine nucleotides,
plays an essential role in the growth and progression of certain tumors. However, there is …
plays an essential role in the growth and progression of certain tumors. However, there is …
Multi-omics data analysis identifies prognostic biomarkers across cancers
E Demir Karaman, Z Işık - Medical Sciences, 2023 - mdpi.com
Combining omics data from different layers using integrative methods provides a better
understanding of the biology of a complex disease such as cancer. The discovery of …
understanding of the biology of a complex disease such as cancer. The discovery of …
25-Hydroxycholesterol 3-sulfate is an endogenous ligand of DNA methyltransferases in hepatocytes
Y Wang, W Lin, JE Brown, L Chen, WM Pandak… - Journal of lipid …, 2021 - ASBMB
Abstract The oxysterol sulfate, 25-hydroxycholesterol 3-sulfate (25HC3S), has been shown
to play an important role in lipid metabolism, inflammatory response, and cell survival …
to play an important role in lipid metabolism, inflammatory response, and cell survival …
Pancancer survival prediction using a deep learning architecture with multimodal representation and integration
Z Fan, Z Jiang, H Liang, C Han - Bioinformatics Advances, 2023 - academic.oup.com
Motivation Use of multi-omics data carrying comprehensive signals about the disease is
strongly desirable for understanding and predicting disease progression, cancer particularly …
strongly desirable for understanding and predicting disease progression, cancer particularly …
Machine learning with the TCGA-HNSC dataset: improving usability by addressing inconsistency, sparsity, and high-dimensionality
Background In the era of precision oncology and publicly available datasets, the amount of
information available for each patient case has dramatically increased. From clinical …
information available for each patient case has dramatically increased. From clinical …