An up-to-date review of biomaterials application in wound management

AG Niculescu, AM Grumezescu - Polymers, 2022 - mdpi.com
Whether they are caused by trauma, illness, or surgery, wounds may occur throughout
anyone's life. Some injuries' complexity and healing difficulty pose important challenges in …

Bioengineered MSC-derived exosomes in skin wound repair and regeneration

H Zhao, Z Li, Y Wang, K Zhou, H Li, S Bi… - Frontiers in Cell and …, 2023 - frontiersin.org
Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers
represent a challenge for clinicians and researchers in many aspects. The treatment …

Immune activated cellular therapy for drug resistant infections: rationale, mechanisms, and implications for veterinary medicine

LM Pezzanite, L Chow, A Strumpf, V Johnson… - Veterinary …, 2022 - mdpi.com
Simple Summary Mesenchymal stromal/stem cells have intrinsic antimicrobial properties,
thus making them attractive as an alternative treatment strategy in chronic, drug-resistant …

Cell secretome strategies for controlled drug delivery and wound-healing applications

R Ibrahim, H Mndlovu, P Kumar, SA Adeyemi… - Polymers, 2022 - mdpi.com
There is significant interest in using stem cells in the management of cutaneous wounds.
However, potential safety, efficacy, and cost problems associated with whole-cell …

A carboxymethyl chitosan/oxidized hyaluronic acid composite hydrogel dressing loading with stem cell exosome for chronic inflammation wounds healing

Y Yue, Y Liu, Y Lin, F Guo, K Cai, S Chen… - International Journal of …, 2024 - Elsevier
Stem cell exosomes (Exo) play an important role in the transformation of macrophages, but
the rapid clearance of Exo in vivo limits their therapeutic effects for chronic inflammation …

Exosomes: a promising avenue for cancer diagnosis beyond treatment

Z Wang, Q Wang, F Qin, J Chen - Frontiers in Cell and …, 2024 - frontiersin.org
Exosomes, extracellular vesicles secreted by cells, have garnered significant attention in
recent years for their remarkable therapeutic potential. These nanoscale carriers can be …

Human mesenchymal stem cell secretomes: factors affecting profiling and challenges in clinical application

NAB Noor Azlan, V Vitus, N Nor Rashid, F Nordin… - Cell and Tissue …, 2024 - Springer
The promising field of regenerative medicine is thrilling as it can repair and restore organs
for various debilitating diseases. Mesenchymal stem cells are one of the main components …

Inhaled placental mesenchymal stromal cell secretome from two-and three-dimensional cell cultures promotes survival and regeneration in acute lung injury model in …

VA Kudinov, RI Artyushev, IM Zurina, ES Zorina… - International Journal of …, 2022 - mdpi.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is a common clinical
problem, leading to significant morbidity and mortality, and no effective pharmacotherapy …

Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models

Y Wang, J Wu, J Chen, C Lu, J Liang… - Bioengineering & …, 2023 - Wiley Online Library
Recovery of skin function remains a significant clinical challenge for deep burns owing to the
severe scar formation and poor appendage regeneration, and stem cell therapy has shown …

Mesenchymal stromal cells isolated from chicken peripheral blood secrete bioactive factors with antimicrobial and regenerative properties

RM Harman, KA Churchill, S Parmar… - Frontiers in Veterinary …, 2022 - frontiersin.org
Mesenchymal stromal cells (MSCs) are adult multipotent progenitor cells that have been
isolated from various tissue sources of many species, primarily mammals. Generally, these …