Primary aldosteronism is an endocrine disorder caused by excessive production of
aldosterone by the adrenal glands, and is recognized as the most important cause of …

The study of adrenal disorders is a key component of scientific research, driven by the
complex innervation, unique structure, and essential functions of the adrenal glands. This …

Background While previous studies indicate that the zonae reticularis (ZR) and glomerulosa
(ZG) diminish with aging, little is known about age-related transformations of the zona …

Recent studies in mouse models have demonstrated that the multi‐cellular rosette structure
of the adrenal zona glomerulosa (ZG) is crucial for aldosterone production by ZG cells …

Background Rewriting the genomes of living organisms has been a long-standing aim in the
biological sciences. The revelation of the CRISPR/Cas9 technology has revolutionized the …

Background Functionality of human adrenal tumors is inferred by CYP11B1 (cortisol
synthase) expression, CYP11B2 (aldosterone synthase) expression, or both …

Background: Aldosterone-producing adenomas (APAs) are a major cause of primary
aldosteronism, a condition of low-renin hypertension, in which aldosterone overproduction is …

Aldosterone producing micronodules (APM) are the predicted precursor to aldosterone
producing adenomas (APA) and can cause primary aldosteronism (PA) in their own right. PA …

With the increasing world human population, the demand for food is also increasing. The
estimated demand for pork in 2050 is 143 million metric tons as opposed to a demand of …

Abstract (EN) Adrenal insufficiency is a life-threatening disease, in which adrenocortical
cells fail to produce adequate amount of steroid hormones, mostly glucocorticoids (cortisol) …