Globally, migraine is a leading cause of disability with a huge impact on both the work and
private life of affected persons. To overcome the societal migraine burden, better treatment …

Migraine is one of the leading causes of disability worldwide, affecting work and social life. It
has been estimated that sales of migraine medicines will reach 12.9 billion USD in 2027. To …

Background: Angiogenesis is a promising strategy for those with peripheral artery disease.
Macrophage-centered inflammation is intended to govern the deficiency of the angiogenic …

Climate change is a growing global issue with many countries and institutions declaring a
climate state of emergency. Excess CO 2 from anthropogenic sources and changes in land …

Mitochondrial abnormalities are primarily seen in morphology, structure and function. They
can cause damage to organs, including the heart, brain and muscle, by various …

Vertebrates need oxygen to survive. The central nervous system has an especially high
energy demand, so brain and retinal neurons quickly die in anoxia. But fish of the genus …

Symbiosis is found throughout nature, but perhaps nowhere is it more fundamental than
mitochondria in all eukaryotes. Since mitochondria were discovered and mechanisms of …

Pheochromocytomas/paragangliomas (PPGLs) are neuroendocrine tumours, mostly
resulting from mutations in predisposing genes. Mutations of succinate dehydrogenase …

Central neurons of the common goldfish (Carassius auratus) are exceptional in their
capacity to survive Ca 2+-induced excitotoxicity and cell death during hypoxia. Horizontal …

Globally, migraine is a leading cause of disability with a huge impact on both the work and
private life of affected persons. To overcome the societal migraine burden, better treatment …