Review of applications and future prospects of stimuli-responsive hydrogel based on thermo-responsive biopolymers in drug delivery systems
S Chatterjee, PC Hui - Polymers, 2021 - mdpi.com
Some of thermo-responsive polysaccharides, namely, cellulose, xyloglucan, and chitosan,
and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol …
and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol …
Nanomaterial-based delivery of vaccine through nasal route: opportunities, challenges, advantages, and limitations
M Kumar, R Dogra, UK Mandal - Journal of Drug Delivery Science and …, 2022 - Elsevier
Mucosal administration especially via the nasal route is a novel and promising technique for
medication and vaccine delivery. Mucosal pathways provide notable benefits that promote …
medication and vaccine delivery. Mucosal pathways provide notable benefits that promote …
Self-assembled lecithin-chitosan nanoparticles improved rotigotine nose-to-brain delivery and brain targeting efficiency
Rotigotine (RTG) is a non-ergoline dopamine agonist and an approved drug for treating
Parkinson's disease. However, its clinical use is limited due to various problems, viz. poor …
Parkinson's disease. However, its clinical use is limited due to various problems, viz. poor …
Optimization and in vivo evaluation of triamcinolone acetonide loaded in situ gel prepared using reacted tamarind seed xyloglucan and kappa-carrageenan for ocular …
In the current work, triamcinolone acetonide (TAA) loaded dual responsive in situ gelling
system was designed and optimized using reacted tamarind seed xyloglucan (RXG) …
system was designed and optimized using reacted tamarind seed xyloglucan (RXG) …
Nose-to-brain delivery of rotigotine redispersible nanosuspension: In vitro and in vivo characterization
P Saha, H Kathuria, MM Pandey - Journal of Drug Delivery Science and …, 2023 - Elsevier
Rotigotine (RTG) is an anti-Parkinson's drug approved by the USFDA to treat motor and non-
motor symptoms of both early and advanced stages of the disease. However, issues like …
motor symptoms of both early and advanced stages of the disease. However, issues like …
Polysaccharide-based platforms for nasal delivery: design, features, and perspectives
E Elmowafy, ME Soliman - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Polysaccharides acceded by the Food and Drug Administration are among the
most exploitable polymers for fabricating nasally applied vehicles containing therapeutically …
most exploitable polymers for fabricating nasally applied vehicles containing therapeutically …
Preparation and Optimization of Liposome Containing Thermosensitive In Situ Nasal Hydrogel System for Brain Delivery of Sumatriptan Succinate
Drug absorption is improved by the intranasal route's wide surface area and avoidance of
first-pass metabolism. For the treatment of central nervous system diseases such as …
first-pass metabolism. For the treatment of central nervous system diseases such as …
Biomaterials for drugs nose–brain transport: a new therapeutic approach for neurological diseases
R Cassano, C Servidio, S Trombino - Materials, 2021 - mdpi.com
In the last years, neurological diseases have resulted in a global health issue, representing
the first cause of disability worldwide. Current therapeutic approaches against neurological …
the first cause of disability worldwide. Current therapeutic approaches against neurological …
Design and evaluation of rufinamide nanocrystals loaded thermoresponsive nasal in situ gelling system for improved drug distribution to brain
Rufinamide (Rufi) is an antiepileptic drug used to manage Lennox-Gastaut Syndrome and
partial seizures. The oral bioavailability of Rufi is less due to its poor solubility and low …
partial seizures. The oral bioavailability of Rufi is less due to its poor solubility and low …
Rufinamide-Loaded Chitosan Nanoparticles in Xyloglucan-Based Thermoresponsive In Situ Gel for Direct Nose to Brain Delivery
In 2004, the US FDA approved Rufinamide, an anti-epileptic drug under the brand name
Banzel®. In 2015, Banzel® received approval for its use in pediatric patients (ages 1–4 …
Banzel®. In 2015, Banzel® received approval for its use in pediatric patients (ages 1–4 …