Keratin intermediate filament proteins are major cytoskeletal components of the mammalian
simple layered columnar epithelium in the gastrointestinal tract. Human colon crypt epithelial …

Keratins make up a major portion of epithelial intermediate filament proteins. The widely
diverse keratins are found in both the small and large intestines. The human intestine mainly …

Caloric restriction (CR) is known to promote health and longevity, likely via modification of
the gut microbiota (GM). However, functional and metabolic changes induced in the GM …

Abstract Keratin 8 (K8) is the main intestinal epithelial intermediate filament protein with
proposed roles for colonic epithelial cell integrity. Here, we used mice lacking K8 in …

Abstract Background Korea Red Ginseng (KRG) has been used as remedies with hepato-
protective effects in liver-related condition. Microbiota related gut-liver axis plays key roles in …

Keratins (K) are intermediate filament proteins important in stress protection and mechanical
support of epithelial tissues. K8, K18 and K19 are the main colonic keratins, and K8 …

The clinical course of IBD, characterized by relapses and remissions, is difficult to predict.
Initial diagnosis can be challenging, and novel disease markers are needed. Keratin 7 (K7) …

Delayed onset of antidepressant action is a shortcoming in depression treatment. Ketamine
and its metabolite (2R, 6R)-hydroxynorketamine (HNK) have emerged as promising rapid …

Ovarian cancer (OC) incidence and mortality peaks at post-menopause while OC risk is
either reduced by parity or increased by nulliparity during fertile life. The long-term effect of …

Keratin (K) 7 is an intermediate filament protein expressed in ducts and glands of simple
epithelial organs and in urothelial tissues. In the pancreas, K7 is expressed in exocrine …