The human eye is a complex organ consisting of multiple compartments with unique and
specialized properties that reflect their varied functions. Although there have been …

The diseases affecting the retina or uvea (iris, ciliary body, or choroid) generate changes in
the biochemical or protein composition of ocular fluids/tissues due to disruption of blood …

Background The vitreous humor is a transparent, gelatinous mass whose main constituent is
water. It plays an important role in providing metabolic nutrient requirements of the lens …

Both exfoliation glaucoma (XFG) and primary open-angle glaucoma (POAG) have been
linked to decreased conventional outflow of aqueous humor (AH). To better understand the …

Isobaric labeling-based proteomics is widely applied in deep proteome quantification.
Among the platforms for isobaric labeled proteomic data analysis, the commercial software …

The aqueous humor is a colorless, transparent fluid that fills the anterior chamber of the eye.
It plays an important role in maintaining the intraocular pressure and providing nourishment …

Primary angle-closure glaucoma (PACG) is a common form of glaucoma in the Far East. Its
defining feature is iridocorneal angle closure. In addition to PACG, indications of angle …

Abnormal development of the ocular anterior segment may lead to a spectrum of clinical
phenotypes ranging from primary congenital glaucoma (PCG) to variable anterior segment …

Pigment epithelial cells (PECs) of the retina (RPE), ciliary body, and iris (IPE) are capable of
altering their phenotype. The main pathway of phenotypic switching of eye PECs in …

Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, and
intraocular pressure (IOP) is an important modifiable risk factor. IOP is a function of aqueous …