[HTML][HTML] Advances in the treatment of Chagas disease: Promising new drugs, plants and targets

P García-Huertas, N Cardona-Castro - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Chagas disease, caused by Trypanosoma cruzi, is treated with only two drugs;
benznidazole and nifurtimox. These drugs have some disadvantages, including their …

A review on antimicrobial botanicals, phytochemicals and natural resistance modifying agents from Apocynaceae family: Possible therapeutic approaches against …

U Anand, S Nandy, A Mundhra, N Das… - Drug Resistance …, 2020 - Elsevier
Accelerated emergence of drug-resistant pathogenic microbes, their unbeatable virulence
and a gradual loss of efficacy of currently used antimicrobial agents over the last decade …

A review of natural products with antileishmanial activity

LG Rocha, J Almeida, RO Macedo, JM Barbosa-Filho - Phytomedicine, 2005 - Elsevier
Infections caused by protozoa of the genus Leishmania are a major worldwide health
problem, with high endemicity in developing countries. The incidence of the disease has …

Leishmaniasis treatment—a challenge that remains: a review

DO Santos, CER Coutinho, MF Madeira, CG Bottino… - Parasitology …, 2008 - Springer
Leishmaniasis is a disease caused by flagellate protozoan Leishmania spp. and represents
an emergent illness with high morbidity and mortality in the tropics and subtropics. Since the …

Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae

E Osorio, GJ Arango, N Jiménez, F Alzate… - Journal of …, 2007 - Elsevier
Ethnobotanical and chemotaxonomical studies for antiparasitic activity of Colombian
Annonaceae were carried out. In vitro antiprotozoal activity of 36 extracts obtained from six …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Current treatment of leishmaniasis: a review

L Monzote - The Open Antimicrobial Agents Journal, 2009 - benthamopen.com
The World Health Organization has classified the leishmaniasis as a major tropical disease.
An effective vaccine against leishmaniasis is not available and chemotherapy is the only …

Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids

AB Oliveira, MF Dolabela, FC Braga… - Anais da Academia …, 2009 - SciELO Brasil
Malaria remains one of the most serious world health problem and the major cause of
mortality and morbidity in the endemic regions. Brazil is among the 30 high-burden countries …

Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal

AS Botsaris - Journal of Ethnobiology and Ethnomedicine, 2007 - Springer
Abstract The archives of Flora Medicinal, an ancient pharmaceutical laboratory that
supported ethnomedical research in Brazil for more than 30 years, were searched for plants …

Chemical composition along with anti-leishmanial and cytotoxic activity of Zataria multiflora

E Saedi Dezaki, H Mahmoudvand… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Natural products and their compounds are some of the most interesting sources of
new drugs. Reviews have reported various pharmacological properties such as …