Pancreatic cancer is a disease that has a very high fatality rate and one of the highest
mortality ratios among all major cancers, remaining the fourth leading cause of cancer …

B‑cell acute lymphoblastic lymphoma (B‑ALL) is a disease found mainly in children and in
young adults. B‑ALL is characterized by the rapid proliferation of poorly differentiated …

Pediatric high-grade gliomas (HGG) are rare aggressive tumors that present a prognostic
and therapeutic challenge. Diffuse midline glioma, H3K27M–mutant is a new entity …

Background Lung cancer patients with KRAS mutation (s) have a poor prognosis due in part
to the development of resistance to currently available therapeutic interventions …

Abstract Background The Pediatric Oncology East and Mediterranean (POEM) network,
through this report, provides a snapshot view of an expected child's treatment journey in five …

Background The prognosis of children with acute monocytic leukemia (AML‐M5) remains
unsatisfactory and the risk profile is still controversial. We aim to investigate the prognostic …

We performed a retrospective analysis of 1415 acute lymphoblastic leukemia children
diagnosed between January 2000 and December 2016 at Children Welfare Teaching …

The extremely low abundance of circulating tumor DNA in blood samples has limited the
development of liquid biopsy techniques for the early diagnosis of major diseases. In this …

Introduction Recent advances in genetic analysis have led to the discovery of novel genetic
subtypes of precursor B‐cell acute lymphoblastic leukemia (B‐ALL) with prognostic …

Purpose The 5-year survival rate of children with acute lymphoblastic leukemia (ALL) is 85–
90%, with a 10–15% rate of treatment failure. Next-generation sequencing (NGS) identified …