In vivo measurements of cutaneous melanin across spatial scales: using multiphoton microscopy and spatial frequency domain spectroscopy

RB Saager, M Balu, V Crosignani… - … of biomedical optics, 2015 - spiedigitallibrary.org
The combined use of nonlinear optical microscopy and broadband reflectance techniques to
assess melanin concentration and distribution thickness in vivo over the full range of …

Estimation of skin optical parameters for real-time hyperspectral imaging applications

A Bjorgan, M Milanic… - Journal of biomedical …, 2014 - spiedigitallibrary.org
Hyperspectral imaging combines high spectral and spatial resolution in one modality. This
imaging technique is a promising tool for objective medical diagnostics. However, to be …

Physiological and structural characterization of human skin in vivo using combined photothermal radiometry and diffuse reflectance spectroscopy

N Verdel, A Marin, M Milanič, B Majaron - Biomedical optics express, 2019 - opg.optica.org
In this proof-of-concept study we combine two optical techniques to enable assessment of
structure and composition of human skin in vivo: Pulsed photothermal radiometry (PPTR) …

Rapid extraction of skin physiological parameters from hyperspectral images using machine learning

T Manojlović, T Tomanič, I Štajduhar, M Milanič - Applied Intelligence, 2023 - Springer
Noninvasive assessment of skin structure using hyperspectral images has been intensively
studied in recent years. Due to the high computational cost of the classical methods, such as …

Suitability of diffusion approximation for an inverse analysis of diffuse reflectance spectra from human skin in vivo

P Naglič, L Vidovič, M Milanič, LL Randeberg… - Osa …, 2019 - opg.optica.org
Diffusion approximation (DA) of the radiative transport equation allows derivation of
enclosed solutions for diffuse reflectance from multi-layer scattering structures, such as …

Noninvasive assessment of skin structure by combined photothermal radiometry and optical spectroscopy: coregistration with multiphoton microscopy

N Verdel, G Lentsch, M Balu, BJ Tromberg… - Applied optics, 2018 - opg.optica.org
We are combining two optical techniques, pulsed photothermal radiometry (PPTR) and
diffuse reflectance spectroscopy (DRS), for noninvasive assessment of the structure and …

Elimination of single-beam substitution error in diffuse reflectance measurements using an integrating sphere

L Vidovič, B Majaron - Journal of biomedical optics, 2014 - spiedigitallibrary.org
Diffuse reflectance spectra (DRS) of biological samples are commonly measured using an
integrating sphere (IS). To account for the incident light spectrum, measurement begins by …

Wavelet based feature extraction and visualization in hyperspectral tissue characterization

M Denstedt, A Bjorgan, M Milanič… - Biomedical optics …, 2014 - opg.optica.org
Hyperspectral images of tissue contain extensive and complex information relevant for
clinical applications. In this work, wavelet decomposition is explored for feature extraction …

Concentric multipixel silicon photodiode array probes for spatially resolved diffuse reflectance spectroscopy

O Senlik, NM Jokerst - IEEE Journal of Selected Topics in …, 2015 - ieeexplore.ieee.org
Spatially resolved diffuse reflectance (SRDR) measurements provide photon path
information, and enable depth-resolved tissue analysis. This paper introduces an innovative …

Age-related changes of dermal scattering coefficient assessed using a noninvasive optical technique

NG Zima, N Verdel, B Majaron - European Conference on …, 2023 - opg.optica.org
We investigate age-related changes of the dermal reduced scattering coefficient in human
skin using a recently introduced methodology for non-invasive characterization of structure …