The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …

MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …

Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful
are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate …

Research over the past decade has suggested important roles for pseudogenes in
physiology and disease. In vitro experiments demonstrated that pseudogenes contribute to …

MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are responsible for RNA
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …

The concept of competitive endogenous RNA (ce RNA) was first proposed by Salmena and
colleagues. Evidence suggests that pseudogene RNA s can act as a 'sponge'through …

Background/Aims: Non-coding RNAs including miRNA and lncRNA had been reported to
regulate gene expression and were both related to cancer progression. MicroRNA-141 (miR …