Microbiota-centered interventions: the next breakthrough in immuno-oncology?

L Derosa, B Routy, A Desilets, R Daillère, S Terrisse… - Cancer Discovery, 2021 - AACR
The cancer–immune dialogue subject to immuno-oncological intervention is profoundly
influenced by microenvironmental factors. Indeed, the mucosal microbiota—and more …

[HTML][HTML] NSCLC immunotherapy efficacy and antibiotic use: a systematic review and meta-analysis

L Lurienne, J Cervesi, L Duhalde… - Journal of Thoracic …, 2020 - Elsevier
Immune checkpoint inhibitors (ICIs) have dramatically improved patient outcomes in a
variety of tumor types, but with variable efficacy. Recent research has suggested that …

Antibiotic use and the efficacy of immune checkpoint inhibitors in cancer patients: a pooled analysis of 2740 cancer patients

XZ Huang, P Gao, YX Song, Y Xu, JX Sun… - …, 2019 - Taylor & Francis
The gut microbiota plays a critical role in the anti-tumor immune response. There is
increasing data showing that antibiotics (ATBs) change the composition of the gut microbiota …

[HTML][HTML] Use of antibiotics is associated with worse clinical outcomes in patients with cancer treated with immune checkpoint inhibitors: A systematic review and meta …

M Tsikala-Vafea, N Belani, K Vieira, H Khan… - International Journal of …, 2021 - Elsevier
Objectives Observational and experimental studies suggest that the use of antibiotics close
to administration of immune checkpoint inhibitors (ICI) can have a negative effect on tumour …

Antibiotic administration shortly before or after immunotherapy initiation is correlated with poor prognosis in solid cancer patients: An up-to-date systematic review and …

M Yang, Y Wang, M Yuan, M Tao, C Kong, H Li… - International …, 2020 - Elsevier
Abstract Objective Immune checkpoint inhibitors (ICIs) have recently achieved inspiring
performance in improving the prognosis of various solid tumors. Gut microbiome plays a …

Effects of antibiotic use on outcomes in cancer patients treated using immune checkpoint inhibitors: a systematic review and meta-analysis

Y Yu, P Zheng, L Gao, H Li, P Tao, D Wang… - Journal of …, 2021 - journals.lww.com
Antibiotic (ATB) use seems to negatively affect the outcomes of immune checkpoint
inhibitors (ICIs). The aim of this review is to clarify whether ATB use influences the efficacy of …

Nutritional assessment and quality of life in patients with non-small cell lung cancer undergoing immunotherapy

T Konstantinidis, C Fragkioudaki… - … Journal of Palliative …, 2023 - magonlinelibrary.com
Background: Patients with metastatic non-small cell lung cancer (NSCLC) often experience
severe eating disorders and other problems because of rapid disease progression and …

[HTML][HTML] Antibiotic exposure windows and the efficacy of immune checkpoint blockers in patients with cancer: a meta-analysis

L Huang, X Chen, L Zhou, Q Xu, J Xie… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: Immune checkpoint blockers (ICBs) improve the survival of patients with
cancer, but primary or acquired drug resistance is inevitable. Intestinal microorganisms play …

Αξιολόγηση της θρέψης και ποιότητας ζωής σε ασθενείς με μη μικροκυτταρικό καρκίνο πνεύμονα υπό ανοσοθεραπεία.

Χ Φραγκιουδάκη - 2020 - apothesis.lib.hmu.gr
Εισαγωγή. Οι ασθενείς με μεταστατικό, μη μικροκυτταρικό καρκίνο πνεύμονα (ΜΜΚΠ)
βιώνουν συχνά διαταραχές θρέψης και άλλα προβλήματα ως συνέπεια της ταχείας εξέλιξης …