In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

Preeclampsia (PE), the leading cause of maternal and fetal morbidity and mortality, is
associated with poor fetal growth, intrauterine growth restriction (IUGR) and low birth weight …

Non-invasive prenatal diagnosis (NIPD) is based on fetal DNA analysis starting from a
simple peripheral blood sample, thus avoiding risks associated with conventional invasive …

Hill M, Finning K, Martin P, Hogg J, Meaney C, Norbury G, Daniels G, Chitty LS. Non‐
invasive prenatal determination of fetal sex: translating research into clinical practice. The …

As the primary interface between maternal and fetal circulations, the placenta is subject to a
myriad of environmental exposures with the capacity to alter placental function and fetal …

SERPINA3 (Serpin peptidase inhibitor clade A member 3), also known as a1-
antichymotrypsin, is a serine protease inhibitor involved in a wide range of biological …

Strong evidence suggests a potential link among epigenetics, microRNAs (miRNAs), and
pregnancy complications. Much research still needs to be carried out to determine whether …

The development of preeclampsia (PE) seriously affects the health of the mother and the
child, but the precise pathogenesis of PE remains elusive. The placenta is considered to …

Multiple environmental, behavioral, and hereditary factors affect pregnancy. Recent studies
suggest that epigenetic modifications, such as DNA methylation (DNAm), affect both …

Dietary deficiencies of folate and other B vitamin cofactors involved in one-carbon
metabolism, together with genetic polymorphisms in key folate–methionine metabolic …