AFM assessing of nanomechanical fingerprints for cancer early diagnosis and classification: from single cell to tissue level

A Stylianou, M Lekka, T Stylianopoulos - Nanoscale, 2018 - pubs.rsc.org
Cancer development and progression are closely associated with changes both in the
mechano-cellular phenotype of cancer and stromal cells and in the extracellular matrix …

The Hertz model in AFM nanoindentation experiments: applications in biological samples and biomaterials

SV Kontomaris - Micro and Nanosystems, 2018 - ingentaconnect.com
AFM nanoindentation is a modern technique which is used for the determination of the
mechanical properties of materials and biomaterials. With regards to the nanoindentation …

The effects of UV irradiation on collagen D‐band revealed by atomic force microscopy

SV Kontomaris, D Yova, A Stylianou, G Balogiannis - Scanning, 2015 - Wiley Online Library
The objective of this paper was to investigate the influence of UV irradiation on collagen D‐
band periodicity by using the AFM imaging and nanoindentation methods. It is well known …

Atomic Force Microscopy for Collagen‐Based Nanobiomaterials

A Stylianou - Journal of Nanomaterials, 2017 - Wiley Online Library
Novel nanobiomaterials are increasingly gaining ground in bioengineering research.
Among the numerous biomaterials, collagen‐nanobiomaterials, such as collagen thin films …

Investigation of the influence of UV irradiation on collagen thin films by AFM imaging

A Stylianou, D Yova, E Alexandratou - Materials Science and Engineering …, 2014 - Elsevier
Collagen is the major fibrous extracellular matrix protein and due to its unique properties, it
has been widely used as biomaterial, scaffold and cell-substrate. The aim of the paper was …

Atomic force microscopy probing of cancer cells and tumor microenvironment components

A Stylianou, T Stylianopoulos - BioNanoScience, 2016 - Springer
Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell
interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix …

Assessing collagen D-band periodicity with atomic force microscopy

A Stylianou - Materials, 2022 - mdpi.com
The collagen superfamily includes more than fifty collagen and/or collagen-like proteins with
fibril-forming collagen type I being the most abundant protein within the extracellular matrix …

A discussion regarding the approximation of cylindrical and spherical shaped samples as half spaces in AFM nanoindentation experiments

SV Kontomaris, A Stylianou, A Malamou… - Materials Research …, 2018 - iopscience.iop.org
A common assumption of nanoidentation experiments is to consider the sample as an
elastic half space due to the simplicity of the analysis regarding the Young's modulus …

How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells …

P Duan, R Toumpaniari, S Partridge, MA Birch… - Materials Science and …, 2018 - Elsevier
This paper presents an investigation of how different culture media (ie basal and osteogenic
media) affect the nanomechanical properties and microstructure of the mineralized matrix …

[PDF][PDF] Duan P, Toumpaniari R, Partridge S, Birch M, Genever PA, Bull SJ, Dalgarno

MCAW KW, J Chen - academia.edu
This paper presents an investigation of how different culture media (ie basal and osteogenic
media) affect the nanomechanical properties and microstructure of the mineralized matrix …