Vaccines meet big data: State-of-the-Art and future prospects. From the classical 3Is (“Isolate–Inactivate–Inject”) vaccinology 1.0 to vaccinology 3.0, vaccinomics, and …

NL Bragazzi, V Gianfredi, M Villarini… - Frontiers in public …, 2018 - frontiersin.org
Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

The Pan-Genome of the Animal Pathogen Corynebacterium pseudotuberculosis Reveals Differences in Genome Plasticity between the Biovar ovis and equi Strains

SC Soares, A Silva, E Trost, J Blom, R Ramos… - PLoS …, 2013 - journals.plos.org
Corynebacterium pseudotuberculosis is a facultative intracellular pathogen and the
causative agent of several infectious and contagious chronic diseases, including caseous …

A journey through the Corynebacterium pseudotuberculosis proteome promotes insights into its functional genome

WM da Silva, N Seyffert, A Silva, V Azevedo - PeerJ, 2021 - peerj.com
Background Corynebacterium pseudotuberculosis is a Gram-positive facultative intracellular
pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants …

[HTML][HTML] Prediction of new vaccine targets in the core genome of Corynebacterium pseudotuberculosis through omics approaches and reverse vaccinology

CL Araújo, J Alves, W Nogueira, LC Pereira… - Gene, 2019 - Elsevier
Corynebacterium pseudotuberculosis is the etiologic agent of veterinary relevance
diseases, such as caseous lymphadenitis, affecting different animal species causing …

Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology

Z Ni, Y Chen, E Ong, Y He - International journal of molecular sciences, 2017 - mdpi.com
As one of the most influential and troublesome human pathogens, Acinetobacter baumannii
(A. baumannii) has emerged with many multidrug-resistant strains. After collecting 33 …

Analyses of the probiotic property and stress resistance-related genes of Lactococcus lactis subsp. lactis NCDO 2118 through comparative genomics and in vitro …

LC Oliveira, TDL Saraiva, WM Silva, UP Pereira… - PLoS …, 2017 - journals.plos.org
Lactococcus lactis subsp. lactis NCDO 2118 was recently reported to alleviate colitis
symptoms via its anti-inflammatory and immunomodulatory activities, which are exerted by …

Recombinant CP40 from Corynebacterium pseudotuberculosis confers protection in mice after challenge with a virulent strain

D Droppa-Almeida, WLP Vivas, KKO Silva… - Vaccine, 2016 - Elsevier
Abstract Background Caseous Lymphadenitis (CLA) is a contagious, infectious, chronic
disease caused by Corynebacterium pseudotuberculosis, which affects mainly sheep and …

Immune-Informatic Analysis and Design of Peptide Vaccine From Multi-epitopes Against Corynebacterium pseudotuberculosis

D Droppa-Almeida, E Franceschi… - … and Biology Insights, 2018 - journals.sagepub.com
Caseous lymphadenitis (CLA) is a disease caused by Corynebacterium pseudotuberculosis
bacteria that affects sheep and goats. The absence of a serologic diagnose is a factor that …

Quadruplex PCR assay for identification of Corynebacterium pseudotuberculosis differentiating biovar Ovis and Equi

S Almeida, EMS Dorneles, C Diniz, V Abreu… - BMC veterinary …, 2017 - Springer
Background Corynebacterium pseudotuberculos is is classified into two biovars, nitrate-
negative biovar Ovis which is the etiologic agent of caseous lymphadenitis in small …

Corynebacterium pseudotuberculosis Pneumonia in a Veterinary Student Infected During Laboratory Work

L Heggelund, P Gaustad, OE Håvelsrud… - Open forum …, 2015 - academic.oup.com
We present a case of Corynebacterium pseudotuberculosis pneumonia in a veterinary
student, with molecular genetic evidence of acquisition during laboratory work, an …