[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness
AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
[HTML][HTML] The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
[HTML][HTML] Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa
Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
[HTML][HTML] VV116 versus nirmatrelvir–ritonavir for oral treatment of Covid-19
Z Cao, W Gao, H Bao, H Feng, S Mei… - … England Journal of …, 2023 - Mass Medical Soc
Background Nirmatrelvir–ritonavir has been authorized for emergency use by many
countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …
countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …
Evolution of the SARS‐CoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission
LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
and are especially important in high-risk individuals where vaccination is not an option …
and are especially important in high-risk individuals where vaccination is not an option …
Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective …
AS Lauring, MW Tenforde, JD Chappell, M Gaglani… - bmj, 2022 - bmj.com
Objectives To characterize the clinical severity of covid-19 associated with the alpha, delta,
and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …
and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …
[HTML][HTML] Modeling transmission of SARS-CoV-2 omicron in China
Having adopted a dynamic zero-COVID strategy to respond to SARS-CoV-2 variants with
higher transmissibility since August 2021, China is now considering whether, and for how …
higher transmissibility since August 2021, China is now considering whether, and for how …
Neutralization of the SARS-CoV-2 Omicron BA. 1 and BA. 2 variants
Neutralization of Omicron BA. 1 and BA. 2 Variants Although two doses of BNT162b2
vaccine produce immunity that wanes over time, the administration of a booster dose …
vaccine produce immunity that wanes over time, the administration of a booster dose …
[HTML][HTML] Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
B Meng, A Abdullahi, IATM Ferreira, N Goonawardane… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …