Sphingosine 1-phosphate receptor modulator therapy for multiple sclerosis: differential downstream receptor signalling and clinical profile effects

J Chun, G Giovannoni, SF Hunter - Drugs, 2021 - Springer
Lysophospholipids are a class of bioactive lipid molecules that produce their effects through
various G protein-coupled receptors (GPCRs). Sphingosine 1-phosphate (S1P) is perhaps …

Cost effectiveness and budget impact of siponimod compared to interferon beta-1a in the treatment of adult patients with secondary progressive multiple sclerosis with …

N Schur, K Gudala, U Vudumula, S Vadapalle… - …, 2021 - Springer
Objective The study aim was to evaluate the cost effectiveness and budget impact of
siponimod compared to interferon beta-1a for adult patients with secondary progressive …