[HTML][HTML] Treatment of liver fibrosis: Past, current, and future
Liver fibrosis accompanies the progression of chronic liver diseases independent of
etiologies, such as hepatitis viral infection, alcohol consumption, and metabolic-associated …
etiologies, such as hepatitis viral infection, alcohol consumption, and metabolic-associated …
Immunomodulation in non-alcoholic fatty liver disease: exploring mechanisms and applications
Z Guo, Q Wu, P Xie, J Wang, W Lv - Frontiers in Immunology, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) exhibits increased lipid enrichment in
hepatocytes. The spectrum of this disease includes stages such as nonalcoholic simple fatty …
hepatocytes. The spectrum of this disease includes stages such as nonalcoholic simple fatty …
GepLiver: an integrative liver expression atlas spanning developmental stages and liver disease phases
Z Li, H Zhang, Q Li, W Feng, X Jia, R Zhou, Y Huang… - Scientific Data, 2023 - nature.com
Chronic liver diseases usually developed through stepwise pathological transitions under
the persistent risk factors. The molecular changes during liver transitions are pivotal to …
the persistent risk factors. The molecular changes during liver transitions are pivotal to …
Immune system dysregulation in the pathogenesis of non-alcoholic steatohepatitis: unveiling the critical role of T and B lymphocytes
Non-alcoholic fatty liver disease (NAFLD), characterized by the excessive accumulation of
fat within the cytoplasm of hepatocytes (exceeding 5% of liver weight) in individuals without …
fat within the cytoplasm of hepatocytes (exceeding 5% of liver weight) in individuals without …
[HTML][HTML] TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma
ML Niese, AL Pajulas, CR Rostron, CCL Cheung… - Mucosal …, 2024 - Elsevier
Multi-cytokine-producing Th9 cells secrete IL-9 and type 2 cytokines and mediate mouse
and human allergic inflammation. However, the cytokines that promote a multi-cytokine …
and human allergic inflammation. However, the cytokines that promote a multi-cytokine …
Role of gut microbiota and immune cells in metabolic-associated fatty liver disease: clinical impact
A Alisi, G McCaughan, H Grønbæk - Hepatology International, 2024 - Springer
In 2020, a revised definition of fatty liver disease associated with metabolic dysfunction
(MAFLD) was proposed to replace non-alcoholic fatty liver (NAFLD). Liver steatosis and at …
(MAFLD) was proposed to replace non-alcoholic fatty liver (NAFLD). Liver steatosis and at …
T cell trafficking in human chronic inflammatory diseases
A Giovenzana, V Codazzi, M Pandolfo, A Petrelli - Iscience, 2024 - cell.com
Circulating T cells, which migrate from the periphery to sites of tissue inflammation, play a
crucial role in the development of various chronic inflammatory conditions. Recent research …
crucial role in the development of various chronic inflammatory conditions. Recent research …