Pedunculopontine nucleus region deep brain stimulation (DBS) is a promising but
experimental therapy for axial motor deficits in Parkinson's disease (PD), particularly gait …

Freezing of gait (FOG) is a common and debilitating, but largely mysterious, symptom of
Parkinson disease. In this review, we will discuss the cerebral substrate of FOG focusing on …

Frontotemporal lobar degeneration causes a spectrum of complex degenerative disorders
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS; the most common
phenotype of corticobasal degeneration) are tauopathies with a relentless course, usually …

In the last quarter of a century, DBS has become an established neurosurgical treatment for
Parkinson's disease (PD), dystonia, and tremors. Improved understanding of brain circuitries …

The ability to generate and control locomotor movements depends on complex interactions
between many areas of the nervous system, the musculoskeletal system, and the …

Dystonia is common in the classic atypical parkinsonian disorders such as multiple system
atrophy, progressive supranuclear palsy and corticobasal degeneration, and to a lesser …

Progressive supranuclear palsy (PSP) is an atypical parkinsonian condition characterized
by a symmetric akinetic–rigid syndrome, early falls, supranuclear gaze palsy, and a …

This brief review resolves a number of persistent conflicts regarding the location and
characteristics of the mesencephalic locomotor region, which has in the past been described …

Falls and gait impairment in Parkinson's Disease (PD) is a leading cause of morbidity and
mortality, significantly impacting quality of life and contributing heavily to disability. Thus far …