Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
Emerging connectivity of programmed cell death pathways and its physiological implications
The removal of functionally dispensable, infected or potentially neoplastic cells is driven by
programmed cell death (PCD) pathways, highlighting their important roles in homeostasis …
programmed cell death (PCD) pathways, highlighting their important roles in homeostasis …
Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract
T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
Dying cells fan the flames of inflammation
K Newton, VM Dixit, N Kayagaki - Science, 2021 - science.org
Inflammatory processes that recruit leukocytes to injured or infected tissues are crucial for
tissue repair and the elimination of pathogens. However, excessive or chronic inflammation …
tissue repair and the elimination of pathogens. However, excessive or chronic inflammation …
Control of cell death in health and disease
N Kayagaki, JD Webster… - Annual Review of …, 2024 - annualreviews.org
Apoptosis, necroptosis, and pyroptosis are genetically programmed cell death mechanisms
that eliminate obsolete, damaged, infected, and self-reactive cells. Apoptosis fragments cells …
that eliminate obsolete, damaged, infected, and self-reactive cells. Apoptosis fragments cells …
[HTML][HTML] Cell death
Cell death supports morphogenesis during development and homeostasis after birth by
removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating …
removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating …
The regulation of the ZBP1‐NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis)
M Zheng, TD Kanneganti - Immunological reviews, 2020 - Wiley Online Library
ZBP1 has been characterized as a critical innate immune sensor of not only viral RNA
products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z‐RNA produced …
products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z‐RNA produced …
Pattern recognition receptors and the host cell death molecular machinery
GP Amarante-Mendes, S Adjemian, LM Branco… - Frontiers in …, 2018 - frontiersin.org
Pattern Recognition Receptors (PRRs) are proteins capable of recognizing molecules
frequently found in pathogens (the so-called Pathogen-Associated Molecular Patterns …
frequently found in pathogens (the so-called Pathogen-Associated Molecular Patterns …
Roles of RIPK3 in necroptosis, cell signaling, and disease
MJ Morgan, YS Kim - Experimental & molecular medicine, 2022 - nature.com
Abstract Receptor-interacting protein kinase-3 (RIPK3, or RIP3) is an essential protein in the
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
[HTML][HTML] Influenza virus Z-RNAs induce ZBP1-mediated necroptosis
Influenza A virus (IAV) is a lytic RNA virus that triggers receptor-interacting serine/threonine-
protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain …
protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain …