Comparative genomics of the major parasitic worms
Nature genetics, 2019 - nature.com
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …
chronic infections of humans and animals, decimate crop production and are a major …
Twenty-five-year research progress in hookworm excretory/secretory products
AMI Abuzeid, X Zhou, Y Huang, G Li - Parasites & vectors, 2020 - Springer
Hookworm infection is a major public health problem that threatens about 500 million people
throughout tropical areas of the world. Adult hookworms survive for many years in the host …
throughout tropical areas of the world. Adult hookworms survive for many years in the host …
Function of lipid binding proteins of parasitic helminths: still a long road
JF Lombardo, JL Pórfido, MS Sisti, AN Giorello… - Parasitology …, 2022 - Springer
Infections with parasitic helminths cause severe debilitating and sometimes lethal diseases
in humans and domestic animals on a global scale. Unable to synthesize de novo their own …
in humans and domestic animals on a global scale. Unable to synthesize de novo their own …
Novel antiinflammatory biologics shaped by parasite–host coevolution
Parasitic helminth infections, while a major cause of neglected tropical disease burden,
negatively correlate with the incidence of immune-mediated inflammatory diseases such as …
negatively correlate with the incidence of immune-mediated inflammatory diseases such as …
Fatty acid- and retinol-binding protein 6 does not control worm fatty acid content in Caenorhabditis elegans but might play a role in Haemonchus contortus parasitism
F Wu, H Wei, X Chen, Z Du, Y Huang, H Shi, Y Yang… - Parasites & …, 2023 - Springer
Background Nematodes have lost the ability to synthesise necessary lipids de novo and
have complementally evolved the capacity to acquire fatty acids and their derivatives from a …
have complementally evolved the capacity to acquire fatty acids and their derivatives from a …
Transcriptome profiling of Cucumis metuliferus infected by Meloidogyne incognita provides new insights into putative defense regulatory network in Cucurbitaceae
J Ling, Z Mao, M Zhai, F Zeng, Y Yang, B Xie - Scientific reports, 2017 - nature.com
Root-knot nematodes (RKN) represent extensive challenges to Cucurbitaceae crops.
However, Cucumis metuliferus (Cm) is known to be resistant to Meloidogyne incognita (Mi) …
However, Cucumis metuliferus (Cm) is known to be resistant to Meloidogyne incognita (Mi) …
The FAR protein family of parasitic nematodes
SC Parks, S Nguyen, MJ Boulanger… - PLoS …, 2022 - journals.plos.org
Fatty acid–and retinol-binding proteins (FARs) belong to a unique family of
excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our …
excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our …
Parasitic nematode fatty acid-and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways
Parasitic nematodes cause significant morbidity and mortality globally. Excretory/secretory
products (ESPs) such as fatty acid-and retinol-binding proteins (FARs) are hypothesized to …
products (ESPs) such as fatty acid-and retinol-binding proteins (FARs) are hypothesized to …
Genus-level evolutionary relationships of FAR proteins reflect the diversity of lifestyles of free-living and parasitic nematodes
D Yuan, S Li, Z Shang, M Wan, Y Lin, Y Zhang, Y Feng… - BMC biology, 2021 - Springer
Background Nematodes are a widespread and diverse group comprising free-living and
parasitic species, some of which have major detrimental effects on crops, animals, and …
parasitic species, some of which have major detrimental effects on crops, animals, and …
Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils
B Zhan, S Arumugam, MW Kennedy… - PLoS neglected …, 2018 - journals.plos.org
Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding
proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm …
proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm …