Metformin is the most widely known anti-hyperglycemic, officially acquired by the USA
government in 1995 and in 2001 it became the most prescribed treatment for type II …

Iodine (III) reagents have gained importance in organic synthesis due to their strong
oxidative properties in addition to several advantages over other related such as, non-toxic …

Abstract Multi‐Drug Resistance (MDR) is one of the most frequent problems observed in the
course of cancer chemotherapy. Cells under treatment, tend to develop survival …

Background A family of 4 H-benzo [d][1, 3] oxazines were obtained from a group of N-(2-
alkynyl) aryl benzamides precursors via gold (I) catalysed chemoselective 6-exo-dig CO …

In this study, we developed palladium-catalyzed dehydrogenative cyclization to transform 1-
(2-aminoaryl)-3-arylpropan-1-ones into 2-arylquinolin-4 (1 H)-ones, also known as aza …

An efficient iodine (III)‐based protocol for the chlorination and catalytic nitration of N‐tosyl
anilines as well as the proposed reaction mechanism is described. The synergistic …

Strategies for introducing halogens and other inorganic groups in aromatic systems, usually
involve non‐general and strong oxidative protocols which resulted in poor functional group …

Nitrogen‐containing drugs represent one of the worldwide most extensive sources of
treatments for different diseases. Indomethacin as example, is one of the most important non …

Metformin is a versatile, biocompatible, and cheap bis‐guanidine used as first response line
in the type II diabetes treatment. Since its first human trials (1956) several structural …

A PhI (OAc) 2/Pd (OAc) 2 system that synergistically promotes the formation of 8-
hydroxyquinoline derivatives from benzoxazoles and alcohols has been developed. The …