Background Human serum albumin is the principal protein in human serum. It participates in
regulation of plasma oncotic pressure and transports endogenous and exogenous ligands …

The effects of low-molecular-weight (< 1000 g/mol) chemicals on biosystems ranging from
membranes to organisms are of interest in medicinal chemistry, chemical biology …

The MHC-related Fc receptor for IgG (FcRn) protects albumin and IgG from degradation by
binding both proteins with high affinity at low pH in the acid endosome and diverting both …

Propofol is the most widely used injectable general anesthetic. Its targets include ligand-
gated ion channels such as the GABA A receptor, but such receptor-channel complexes …

The market for commercially available isothermal titration calorimeters continues to grow as
new applications and methodologies are developed. Concomitantly the number of users …

Perfluorocarboxylic acids (PFCAs) of chain length greater than seven carbon atoms
bioconcentrate in the livers of fish. However, a mechanistic cause for the empirically …

Measurement of drug concentrations in biological samples is of utmost importance in many
research areas. The information about the amount of drug in a biological sample can be …

Two fluorescence modes were combined to analyze the binding properties of terminally
substituted alkanes (CnX, X= COOH, OH, CHO, NH2) to human serum albumin (HSA). A …

Cyclic peptides, with unique structural features, have emerged as new candidates for drug
discovery; their association with human serum albumin (HSA; long blood half-life) is crucial …

We report the synthesis, spectroscopic properties and intracellular imaging of recombinant
antibody single chain fragment (scFv) conjugates with photosensitizers used for …