[HTML][HTML] Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden

D Hashim, E Genden, M Posner, M Hashibe… - Annals of …, 2019 - Elsevier
Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has
increased by 10% over the past few decades. Little over half of patients who develop HNCs …

The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas

E Benson, R Li, D Eisele, C Fakhry - Oral oncology, 2014 - Elsevier
Human papillomavirus (HPV) is etiologically responsible for a distinct subset of head and
neck squamous cell cancers (HNSCCs). HPV-positive HNSCCs (HPV-HNSCCs) most …

Molecular classification identifies a subset of human papillomavirus–associated oropharyngeal cancers with favorable prognosis

PM Weinberger, Z Yu, BG Haffty, D Kowalski… - Journal of clinical …, 2006 - ascopubs.org
Purpose We sought to determine the prevalence of biologically relevant human
papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OSCC). Retinoblastoma …

p16 positive oropharyngeal squamous cell carcinoma: an entity with a favorable prognosis regardless of tumor HPV status

JS Lewis Jr, WL Thorstad, RD Chernock… - The American journal …, 2010 - journals.lww.com
Background In the human papillomavirus (HPV) era, the best way to assess oropharyngeal
squamous carcinomas (SCC) for risk stratification is not clear. Many recommend use of both …

High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma

L Licitra, F Perrone, P Bossi, S Suardi… - Journal of Clinical …, 2006 - ascopubs.org
Purpose Human papillomavirus (HPV) DNA tumors actively integrating the E6 and E7
oncogenes have a distinct biologic behavior resulting in a more favorable prognosis. To …

p16 expression as a surrogate marker for HPV‐related oropharyngeal carcinoma: a guide for interpretative relevance and consistency

AK El‐Naggar, WH Westra - Head & neck, 2012 - Wiley Online Library
Recent studies of oropharyngeal carcinoma have reported remarkable correlation between
integrated human papillomavirus (HPV) viral detection and p16 protein overexpression in …

High-risk human papillomavirus E6/E7 mRNA detection by a novel in situ hybridization assay strongly correlates with p16 expression and patient outcomes in …

OC Ukpo, JJ Flanagan, XJ Ma, Y Luo… - The American journal …, 2011 - journals.lww.com
Human papillomavirus (HPV) is established as causative in oropharyngeal squamous cell
carcinomas (OSCCs), being detected in 50% to 80% of tumors by DNA in situ hybridization …

Human papillomavirus as a marker of the natural history and response to therapy of head and neck squamous cell carcinoma

KK Ang, EM Sturgis - Seminars in radiation oncology, 2012 - Elsevier
There has been a gradual change in the demographics of head and neck carcinoma.
Although relatively uncommon, the incidence of oropharyngeal carcinoma has been …

Combined analysis of HPV‐DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer

N Reimers, HU Kasper, SJ Weissenborn… - … journal of cancer, 2007 - Wiley Online Library
Molecular prognostic indicators for oropharyngeal squamous cell carcinoma (OSCC),
including HPV‐DNA detection, epidermal growth factor receptor (EGFR) and p16 …

p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma

JS Lewis - Head and neck pathology, 2012 - Springer
It is widely acknowledged that human papillomavirus (HPV)-related oropharyngeal
carcinoma is a biologically unique form of head and neck cancer that should be singled out …